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High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery.

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Title: High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery.
Authors: Howard CJ; Octant, Inc, Emeryville, United States., Abell NS; Octant, Inc, Emeryville, United States., Osuna BA; Octant, Inc, Emeryville, United States., Jones EM; Octant, Inc, Emeryville, United States., Chan LY; Octant, Inc, Emeryville, United States., Chan H; Octant, Inc, Emeryville, United States., Artis DR; Octant, Inc, Emeryville, United States., Asfaha JB; Octant, Inc, Emeryville, United States., Bloom JS; Department of Human Genetics and Department of Computational Medicine, University of California, Los Angeles, Los Angeles, United States.; Howard Hughes Medical Institute, Chevy Chase, United States., Cooper AR; Octant, Inc, Emeryville, United States., Liao A; Octant, Inc, Emeryville, United States., Mahdavi E; Octant, Inc, Emeryville, United States., Mohammed N; Octant, Inc, Emeryville, United States., Su AL; Octant, Inc, Emeryville, United States., Uribe GA; Octant, Inc, Emeryville, United States., Kosuri S; Octant, Inc, Emeryville, United States., Dickel DE; Octant, Inc, Emeryville, United States., Lubock NB; Octant, Inc, Emeryville, United States.
Source: ELife [Elife] 2025 Apr 09; Vol. 13. Date of Electronic Publication: 2025 Apr 09.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
Database: MEDLINE Ultimate
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