Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study.

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Title: Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study.
Authors: Rayner F; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Hiu S; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK., Melville A; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Bigirumurame T; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Anderson A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Dyke B; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK., Kerrigan S; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., McGucken A; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Prichard J; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Shahrokhabadi MS; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Hilkens CMU; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK., Buckley CD; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK., McInnes IB; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Ng WF; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Goodyear C; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK., Teare D; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK., Filer A; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK., Siebert S; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.; NHS Greater Glasgow and Clyde, Glasgow, UK., Raza K; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.; Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK., Pratt A; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Baker KF; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Isaacs J; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK john.isaacs@ncl.ac.uk.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Source: BMJ open [BMJ Open] 2025 Apr 09; Vol. 15 (4), pp. e092478. Date of Electronic Publication: 2025 Apr 09.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
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  Data: Clinical predictors of flare and drug-free remission in rheumatoid arthritis: preliminary results from the prospective BIO-FLARE experimental medicine study.
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  Data: <searchLink fieldCode="AU" term="%22Rayner+F%22">Rayner F</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hiu+S%22">Hiu S</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.; Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Melville+A%22">Melville A</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Bigirumurame+T%22">Bigirumurame T</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Anderson+A%22">Anderson A</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Dyke+B%22">Dyke B</searchLink>; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Kerrigan+S%22">Kerrigan S</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22McGucken+A%22">McGucken A</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Prichard+J%22">Prichard J</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Shahrokhabadi+MS%22">Shahrokhabadi MS</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hilkens+CMU%22">Hilkens CMU</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Buckley+CD%22">Buckley CD</searchLink>; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.; Kennedy Institute of Rheumatology, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McInnes+IB%22">McInnes IB</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Ng+WF%22">Ng WF</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Goodyear+C%22">Goodyear C</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Teare+D%22">Teare D</searchLink>; Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Filer+A%22">Filer A</searchLink>; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Siebert+S%22">Siebert S</searchLink>; Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK.; NHS Greater Glasgow and Clyde, Glasgow, UK.<br /><searchLink fieldCode="AU" term="%22Raza+K%22">Raza K</searchLink>; Institute of Inflammation and Ageing, NIHR Birmingham Biomedical Research Centre, Birmingham, UK.; Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Pratt+A%22">Pratt A</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Baker+KF%22">Baker KF</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Isaacs+J%22">Isaacs J</searchLink>; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK john.isaacs@ncl.ac.uk.; Musculoskeletal Unit, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
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  Data: <searchLink fieldCode="JN" term="%22101552874%22">BMJ open</searchLink> [BMJ Open] 2025 Apr 09; Vol. 15 (4), pp. e092478. <i>Date of Electronic Publication: </i>2025 Apr 09.
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