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Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.

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Title: Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
Authors: Petty LE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Chen HH; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, ROC., Frankel EG; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Zhu W; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Downie CG; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lin P; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Sharma P; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Zhang X; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Scartozzi AC; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Roshani R; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Landman JM; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Bowden DW; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK., Mahajan A; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK., McCarthy MI; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Ng MCY; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Sim X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore., Spracklen CN; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology and Biostatistics, University of Massachusetts-Amherst, Amherst, MA, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK., Preuss M; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Nadkarni GN; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso-Plattner-Institut, Potsdam, Germany., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Tan J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Ipp E; Division of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Genter P; Division of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Emery LS; Department of Biostatistics, University of Washington, Seattle, WA, USA., Louie T; Department of Biostatistics, University of Washington, Seattle, WA, USA., Sofer T; Departments of Medicine and Biostatistics, Harvard University, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA., Stilp AM; Department of Biostatistics, University of Washington, Seattle, WA, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Xiang AH; Department of Research & Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA., Buchanan TA; Department of Medicine, Division of Endocrine, Keck School of Medicine of USC, Los Angeles, CA, USA., Roll K; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-, Salem, NC, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Norris JM; Department of Epidemiology, University of Colorado Denver, Aurora, CO, USA., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Nousome D; Department of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Varma R; Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, CA, USA., McKean-Cowdin R; Department of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Hai Y; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Hsueh W; Department of Internal Medicine, Diabetes and Metabolism Research Center, Ohio State University Wexner Medical Center, Columbus, OH, USA., Sandow K; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Parra EJ; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada., Cruz M; Unidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico., Valladares-Salgado A; Unidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico., Wacher-Rodarte N; Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Goodarzi MO; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Bertoni A; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA., Raffel LJ; Department of Pediatrics, Division of Medical Genetics, UCI Irvine School of Medicine, Irvine, CA, USA., Nadler JL; Department of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA., Kandeel FR; Departments of Clinical Diabetes, Endocrinology & Metabolism and Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA., Duggirala R; Human Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA., Blangero J; Human Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA., Lehman DM; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., DeFronzo RA; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA., Thameem F; Department of Biochemistry, Faculty of Medicine, Health Science Center, Kuwait University, Safat, Kuwait., Wang Y; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Gahagan S; Division of Academic General Pediatrics, Child Development and Community Health, University of California at San Diego, San Diego, CA, USA., Blanco E; College y Escuela de Salud Pública, Pontificia Universidad Católica de Chile, Santiago, Chile., Burrows R; Department of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile., Huerta-Chagoya A; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Florez JC; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Tusie-Luna T; Unidad de Biología Molecular y Medicina Genómica, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., González-Villalpando C; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Pública, Mexico City, Mexico., Orozco L; Instituto Nacional de Medicina Genómica, Mexico City, Mexico., Haiman CA; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA., Hanis CL; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Rohde R; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Whitsel EA; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Kooperberg C; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Li Y; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Duan Q; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lee M; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA., Correa-Burrows P; Department of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile., Fried SK; Diabetes, Obesity Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., McCormick JB; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA., Fisher-Hoch SP; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA., Gamazon ER; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Clare Hall & MRC Epidemiology Unit, University of Cambridge, Cambridge, UK., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK., Mercader JM; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA., Highland HM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Below JE; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. jennifer.e.below@vanderbilt.edu.
Corporate Authors: DIAMANTE Hispanic/Latino Consortium, Global Hispanic Lipids Consortium
Source: Nature communications [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3438. Date of Electronic Publication: 2025 Apr 11.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
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  Data: <searchLink fieldCode="AU" term="%22Petty+LE%22">Petty LE</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Chen+HH%22">Chen HH</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Frankel+EG%22">Frankel EG</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Zhu+W%22">Zhu W</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Downie+CG%22">Downie CG</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Graff+M%22">Graff M</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lin+P%22">Lin P</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sharma+P%22">Sharma P</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Scartozzi+AC%22">Scartozzi AC</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Roshani+R%22">Roshani R</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Landman+JM%22">Landman JM</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Boehnke+M%22">Boehnke M</searchLink>; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Bowden+DW%22">Bowden DW</searchLink>; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Chambers+JC%22">Chambers JC</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Mahajan+A%22">Mahajan A</searchLink>; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22McCarthy+MI%22">McCarthy MI</searchLink>; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ng+MCY%22">Ng MCY</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Center for Precision Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Sim+X%22">Sim X</searchLink>; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Spracklen+CN%22">Spracklen CN</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Epidemiology and Biostatistics, University of Massachusetts-Amherst, Amherst, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital, London North West Healthcare NHS Trust, London, UK.<br /><searchLink fieldCode="AU" term="%22Preuss+M%22">Preuss M</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Bottinger+EP%22">Bottinger EP</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Nadkarni+GN%22">Nadkarni GN</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Digital Health Center, Hasso-Plattner-Institut, Potsdam, Germany.<br /><searchLink fieldCode="AU" term="%22Loos+RJF%22">Loos RJF</searchLink>; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chen+YI%22">Chen YI</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tan+J%22">Tan J</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ipp+E%22">Ipp E</searchLink>; Division of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Genter+P%22">Genter P</searchLink>; Division of Endocrinology & Metabolism, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Emery+LS%22">Emery LS</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Louie+T%22">Louie T</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Sofer+T%22">Sofer T</searchLink>; Departments of Medicine and Biostatistics, Harvard University, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stilp+AM%22">Stilp AM</searchLink>; Department of Biostatistics, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+KD%22">Taylor KD</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xiang+AH%22">Xiang AH</searchLink>; Department of Research & Evaluation, Division of Biostatistics Research, Kaiser Permanente of Southern California, Pasadena, CA, USA.<br /><searchLink fieldCode="AU" term="%22Buchanan+TA%22">Buchanan TA</searchLink>; Department of Medicine, Division of Endocrine, Keck School of Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Roll+K%22">Roll K</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gao+C%22">Gao C</searchLink>; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-, Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Palmer+ND%22">Palmer ND</searchLink>; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Norris+JM%22">Norris JM</searchLink>; Department of Epidemiology, University of Colorado Denver, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Wagenknecht+LE%22">Wagenknecht LE</searchLink>; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Nousome+D%22">Nousome D</searchLink>; Department of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Varma+R%22">Varma R</searchLink>; Southern California Eye Institute, CHA Hollywood Presbyterian Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22McKean-Cowdin+R%22">McKean-Cowdin R</searchLink>; Department of Preventative Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Guo+X%22">Guo X</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hai+Y%22">Hai Y</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hsueh+W%22">Hsueh W</searchLink>; Department of Internal Medicine, Diabetes and Metabolism Research Center, Ohio State University Wexner Medical Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Sandow+K%22">Sandow K</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Parra+EJ%22">Parra EJ</searchLink>; Department of Anthropology, University of Toronto at Mississauga, Mississauga, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Cruz+M%22">Cruz M</searchLink>; Unidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Valladares-Salgado+A%22">Valladares-Salgado A</searchLink>; Unidad de Investigación Médica en Bioquimica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Wacher-Rodarte+N%22">Wacher-Rodarte N</searchLink>; Unidad de Investigación Médica en Epidemiologia Clinica, Hospital de Especialidades, Centro Medico Nacional Siglo XXI, IMSS, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Rotter+JI%22">Rotter JI</searchLink>; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA.<br /><searchLink fieldCode="AU" term="%22Goodarzi+MO%22">Goodarzi MO</searchLink>; Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Rich+SS%22">Rich SS</searchLink>; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA.<br /><searchLink fieldCode="AU" term="%22Bertoni+A%22">Bertoni A</searchLink>; Department of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Raffel+LJ%22">Raffel LJ</searchLink>; Department of Pediatrics, Division of Medical Genetics, UCI Irvine School of Medicine, Irvine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Nadler+JL%22">Nadler JL</searchLink>; Department of Medicine and Pharmacology, New York Medical College, Valhalla, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kandeel+FR%22">Kandeel FR</searchLink>; Departments of Clinical Diabetes, Endocrinology & Metabolism and Translational Research and Cellular Therapeutics, City of Hope, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Duggirala+R%22">Duggirala R</searchLink>; Human Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA.<br /><searchLink fieldCode="AU" term="%22Blangero+J%22">Blangero J</searchLink>; Human Genetics and STDOI, University of Texas Rio Grande Valley, Edinburg, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lehman+DM%22">Lehman DM</searchLink>; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22DeFronzo+RA%22">DeFronzo RA</searchLink>; Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.<br /><searchLink fieldCode="AU" term="%22Thameem+F%22">Thameem F</searchLink>; Department of Biochemistry, Faculty of Medicine, Health Science Center, Kuwait University, Safat, Kuwait.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Gahagan+S%22">Gahagan S</searchLink>; Division of Academic General Pediatrics, Child Development and Community Health, University of California at San Diego, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Blanco+E%22">Blanco E</searchLink>; College y Escuela de Salud Pública, Pontificia Universidad Católica de Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Burrows+R%22">Burrows R</searchLink>; Department of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Huerta-Chagoya+A%22">Huerta-Chagoya A</searchLink>; Consejo Nacional de Ciencia y Tecnología (CONACYT), Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Florez+JC%22">Florez JC</searchLink>; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Tusie-Luna+T%22">Tusie-Luna T</searchLink>; Unidad de Biología Molecular y Medicina Genómica, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México/Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22González-Villalpando+C%22">González-Villalpando C</searchLink>; Centro de Estudios en Diabetes, Unidad de Investigacion en Diabetes y Riesgo Cardiovascular, Centro de Investigacion en Salud Poblacional, Instituto Nacional de Salud Pública, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Orozco+L%22">Orozco L</searchLink>; Instituto Nacional de Medicina Genómica, Mexico City, Mexico.<br /><searchLink fieldCode="AU" term="%22Haiman+CA%22">Haiman CA</searchLink>; Department of Population and Public Health Sciences, Keck School of Medicine of USC, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hanis+CL%22">Hanis CL</searchLink>; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rohde+R%22">Rohde R</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Whitsel+EA%22">Whitsel EA</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Reiner+AP%22">Reiner AP</searchLink>; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Kooperberg+C%22">Kooperberg C</searchLink>; Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Duan+Q%22">Duan Q</searchLink>; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.<br /><searchLink fieldCode="AU" term="%22Correa-Burrows+P%22">Correa-Burrows P</searchLink>; Department of Public Health Nutrition, Institute of Nutrition and Food Technology, University of Chile, Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Fried+SK%22">Fried SK</searchLink>; Diabetes, Obesity Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22North+KE%22">North KE</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22McCormick+JB%22">McCormick JB</searchLink>; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.<br /><searchLink fieldCode="AU" term="%22Fisher-Hoch+SP%22">Fisher-Hoch SP</searchLink>; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Brownsville Regional Campus, Brownsville, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gamazon+ER%22">Gamazon ER</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Clare Hall & MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Morris+AP%22">Morris AP</searchLink>; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Mercader+JM%22">Mercader JM</searchLink>; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Programs in Metabolism and Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; Diabetes Unit and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Highland+HM%22">Highland HM</searchLink>; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.<br /><searchLink fieldCode="AU" term="%22Below+JE%22">Below JE</searchLink>; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. jennifer.e.below@vanderbilt.edu.
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  Data: <searchLink fieldCode="CA" term="%22DIAMANTE+Hispanic%2FLatino+Consortium%22">DIAMANTE Hispanic/Latino Consortium</searchLink><br /><searchLink fieldCode="CA" term="%22Global+Hispanic+Lipids+Consortium%22">Global Hispanic Lipids Consortium</searchLink>
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Apr 11; Vol. 16 (1), pp. 3438. <i>Date of Electronic Publication: </i>2025 Apr 11.
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      – TitleFull: Large-scale multi-omics analyses in Hispanic/Latino populations identify genes for cardiometabolic traits.
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