A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning.
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| Title: | A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning. |
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| Authors: | Gutfleisch M; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany. matthias.gutfleisch@augen-franziskus.de.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany. matthias.gutfleisch@augen-franziskus.de., Heimes-Bussmann B; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany., Aydin S; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; deepeye Medical GmbH, Munich, Germany., Petrovic R; deepeye Medical GmbH, Munich, Germany., Loktyushin A; deepeye Medical GmbH, Munich, Germany., Ohji M; Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga, Japan., Takahashi K; School of Medicine, Kansai Medical University, Hirakata City, Osaka, Japan., Okada AA; School of Medicine, Kyorin University, Mitaka-Shi, Tokyo, Japan., Scholz P; Bayer Vital GmbH, Leverkusen, Germany., Youssef H; Bayer Middle East FZE, Dubai, United Arab Emirates., Bauer-Steinhusen U; Bayer Vital GmbH, Leverkusen, Germany., Machewitz T; Bayer AG, Berlin, Germany., Rothaus K; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany., Lommatzsch A; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; Department of Ophthalmology, University Duisburg-Essen, Essen, Germany.; Achim Wessing Institute of Ophthalmic Diagnostic, University Duisburg-Essen, Essen, Germany. |
| Source: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2025 Jul; Vol. 263 (7), pp. 1885-1897. Date of Electronic Publication: 2025 Apr 10. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Clinical Trial, Phase IV |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8205248 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-702X (Electronic) Linking ISSN: 0721832X NLM ISO Abbreviation: Graefes Arch Clin Exp Ophthalmol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1435-702X |
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| DOI: | 10.1007/s00417-025-06812-x |
