A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning.
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| Title: | A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning. |
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| Authors: | Gutfleisch M; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany. matthias.gutfleisch@augen-franziskus.de.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany. matthias.gutfleisch@augen-franziskus.de., Heimes-Bussmann B; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany., Aydin S; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; deepeye Medical GmbH, Munich, Germany., Petrovic R; deepeye Medical GmbH, Munich, Germany., Loktyushin A; deepeye Medical GmbH, Munich, Germany., Ohji M; Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga, Japan., Takahashi K; School of Medicine, Kansai Medical University, Hirakata City, Osaka, Japan., Okada AA; School of Medicine, Kyorin University, Mitaka-Shi, Tokyo, Japan., Scholz P; Bayer Vital GmbH, Leverkusen, Germany., Youssef H; Bayer Middle East FZE, Dubai, United Arab Emirates., Bauer-Steinhusen U; Bayer Vital GmbH, Leverkusen, Germany., Machewitz T; Bayer AG, Berlin, Germany., Rothaus K; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany., Lommatzsch A; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; Department of Ophthalmology, University Duisburg-Essen, Essen, Germany.; Achim Wessing Institute of Ophthalmic Diagnostic, University Duisburg-Essen, Essen, Germany. |
| Source: | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie [Graefes Arch Clin Exp Ophthalmol] 2025 Jul; Vol. 263 (7), pp. 1885-1897. Date of Electronic Publication: 2025 Apr 10. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Clinical Trial, Phase IV |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 8205248 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-702X (Electronic) Linking ISSN: 0721832X NLM ISO Abbreviation: Graefes Arch Clin Exp Ophthalmol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40210713 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gutfleisch+M%22">Gutfleisch M</searchLink>; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany. matthias.gutfleisch@augen-franziskus.de.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany. matthias.gutfleisch@augen-franziskus.de.<br /><searchLink fieldCode="AU" term="%22Heimes-Bussmann+B%22">Heimes-Bussmann B</searchLink>; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Aydin+S%22">Aydin S</searchLink>; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; deepeye Medical GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Petrovic+R%22">Petrovic R</searchLink>; deepeye Medical GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Loktyushin+A%22">Loktyushin A</searchLink>; deepeye Medical GmbH, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Ohji+M%22">Ohji M</searchLink>; Shiga University of Medical Science, Seta Tsukinowa-Cho, Otsu, Shiga, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; School of Medicine, Kansai Medical University, Hirakata City, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Okada+AA%22">Okada AA</searchLink>; School of Medicine, Kyorin University, Mitaka-Shi, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Scholz+P%22">Scholz P</searchLink>; Bayer Vital GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Youssef+H%22">Youssef H</searchLink>; Bayer Middle East FZE, Dubai, United Arab Emirates.<br /><searchLink fieldCode="AU" term="%22Bauer-Steinhusen+U%22">Bauer-Steinhusen U</searchLink>; Bayer Vital GmbH, Leverkusen, Germany.<br /><searchLink fieldCode="AU" term="%22Machewitz+T%22">Machewitz T</searchLink>; Bayer AG, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Rothaus+K%22">Rothaus K</searchLink>; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.<br /><searchLink fieldCode="AU" term="%22Lommatzsch+A%22">Lommatzsch A</searchLink>; Department of Ophthalmology, St Franziskus-Hospital, Münster, Germany.; M3 Macula Monitor Münster GmbH & Co KG, Münster, Germany.; Department of Ophthalmology, University Duisburg-Essen, Essen, Germany.; Achim Wessing Institute of Ophthalmic Diagnostic, University Duisburg-Essen, Essen, Germany. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228205248%22">Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie</searchLink> [Graefes Arch Clin Exp Ophthalmol] 2025 Jul; Vol. 263 (7), pp. 1885-1897. <i>Date of Electronic Publication: </i>2025 Apr 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase III; Multicenter Study; Clinical Trial, Phase IV – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>8205248 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1435-702X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220721832X%22">0721832X </searchLink><i>NLM ISO Abbreviation: </i>Graefes Arch Clin Exp Ophthalmol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40210713 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00417-025-06812-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1885 Titles: – TitleFull: A post-hoc analysis of intravitreal aflibercept-treated nAMD patients from ARIES & ALTAIR: predicting treatment intervals and frequency for aflibercept treat-and-extend therapy regimen using machine learning. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gutfleisch M – PersonEntity: Name: NameFull: Heimes-Bussmann B – PersonEntity: Name: NameFull: Aydin S – PersonEntity: Name: NameFull: Petrovic R – PersonEntity: Name: NameFull: Loktyushin A – PersonEntity: Name: NameFull: Ohji M – PersonEntity: Name: NameFull: Takahashi K – PersonEntity: Name: NameFull: Okada AA – PersonEntity: Name: NameFull: Scholz P – PersonEntity: Name: NameFull: Youssef H – PersonEntity: Name: NameFull: Bauer-Steinhusen U – PersonEntity: Name: NameFull: Machewitz T – PersonEntity: Name: NameFull: Rothaus K – PersonEntity: Name: NameFull: Lommatzsch A IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2025 Jul Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1435-702X Numbering: – Type: volume Value: 263 – Type: issue Value: 7 Titles: – TitleFull: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Type: main |
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