Functional organotypic human lymph node model with native immune cells benefits from fibroblastic reticular cell enrichment.
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| Title: | Functional organotypic human lymph node model with native immune cells benefits from fibroblastic reticular cell enrichment. |
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| Authors: | Morrison AI; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands., Kuipers JE; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands., Roest HP; Department of Surgery, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015GD, Rotterdam, The Netherlands., van der Laan LJW; Department of Surgery, Erasmus MC Transplant Institute, University Medical Center Rotterdam, Dr. Molewaterplein 40, 3015GD, Rotterdam, The Netherlands., de Winde CM; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands.; Cancer Center Amsterdam, Amsterdam, The Netherlands., Koning JJ; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands., Gibbs S; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands.; Department Oral Cell Biology, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit, Amsterdam, The Netherlands., Mebius RE; Molecular Cell Biology & Immunology, Amsterdam UMC Location Vrije Universiteit Amsterdam, De Boelelaan, 1117, Amsterdam, The Netherlands. r.mebius@amsterdamumc.nl.; Amsterdam Institute for Immunology and Infectious Diseases, Amsterdam, The Netherlands. r.mebius@amsterdamumc.nl. |
| Source: | Scientific reports [Sci Rep] 2025 Apr 10; Vol. 15 (1), pp. 12233. Date of Electronic Publication: 2025 Apr 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-95031-9 |
