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Comparison of Three Mathematical Models of the Pharmacokinetics of Heparin to Guide the Use of Protamine in a Large Simulated Cohort of Patients.

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Title: Comparison of Three Mathematical Models of the Pharmacokinetics of Heparin to Guide the Use of Protamine in a Large Simulated Cohort of Patients.
Authors: Vander Zwaag S; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany., Kukel I; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany., Petrov A; Department of Cardiac Surgery, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany., Fassl J; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany.
Source: Seminars in cardiothoracic and vascular anesthesia [Semin Cardiothorac Vasc Anesth] 2025 Dec; Vol. 29 (4), pp. 258-264. Date of Electronic Publication: 2025 Apr 10.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Sage Publications Country of Publication: United States NLM ID: 9807630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-5596 (Electronic) Linking ISSN: 10892532 NLM ISO Abbreviation: Semin Cardiothorac Vasc Anesth Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Vander+Zwaag+S%22">Vander Zwaag S</searchLink>; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Kukel+I%22">Kukel I</searchLink>; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Petrov+A%22">Petrov A</searchLink>; Department of Cardiac Surgery, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Fassl+J%22">Fassl J</searchLink>; Department of Cardiac Anaesthesiology, Heart Centre Dresden, TUD Dresden University of Technology, Dresden, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Sage+Publications%22">Sage Publications </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9807630 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1940-5596 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210892532%22">10892532 </searchLink><i>NLM ISO Abbreviation: </i>Semin Cardiothorac Vasc Anesth <i>Subsets: </i>MEDLINE
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        Text: English
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              Text: 2025 Dec
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