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CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia.

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Title: CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia.
Authors: Klimovich B; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany., Anton L; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany., Jung J; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea., Lim Y; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea., Lee B; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea., Won J; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea., Zekri L; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany., Chashchina A; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany., Pflügler M; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany., Heitmann JS; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany., Jung G; Department of Immunology, Institute for Cell Biology, Eberhard Karls Universität Tübingen, Tübingen, Germany., Salih HR; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; German Cancer Consortium Deutsche Konsortium für Translationale Krebsforschung (DKTK), partner site Tübingen, a partnership between Deutsche Krebsforschungszentrum (DKFZ) and University Hospital Tübingen, Tübingen, Germany.
Source: Frontiers in immunology [Front Immunol] 2025 Mar 27; Vol. 16, pp. 1561823. Date of Electronic Publication: 2025 Mar 27 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CLEC12A-directed immunocytokine with target cell-restricted IL-15 activity for treatment of acute myeloid leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Klimovich+B%22">Klimovich B</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Anton+L%22">Anton L</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jung+J%22">Jung J</searchLink>; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lim+Y%22">Lim Y</searchLink>; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+B%22">Lee B</searchLink>; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Won+J%22">Won J</searchLink>; ABL Bio Inc., Seongnam-si, Gyeonggi-do, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Zekri+L%22">Zekri L</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Chashchina+A%22">Chashchina A</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Pflügler+M%22">Pflügler M</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Heitmann+JS%22">Heitmann JS</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC 2180) 'Image-Guided and Functionally Instructed Tumor Therapies', Eberhard Karls University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jung+G%22">Jung G</searchLink>; Department of Immunology, Institute for Cell Biology, Eberhard Karls Universität Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Salih+HR%22">Salih HR</searchLink>; Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany.; German Cancer Consortium Deutsche Konsortium für Translationale Krebsforschung (DKTK), partner site Tübingen, a partnership between Deutsche Krebsforschungszentrum (DKFZ) and University Hospital Tübingen, Tübingen, Germany.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Frontiers+Research+Foundation]%22">Frontiers Research Foundation] </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101560960 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1664-3224 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2216643224%22">16643224 </searchLink><i>NLM ISO Abbreviation: </i>Front Immunol <i>Subsets: </i>MEDLINE
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