ABBV-712-induced cardiac pathology in rats is related to off-target-driven acute vasodilation, tachycardia, and increased cardiac contractility. - Kohnken R; Fossey S; Buck WR; Segreti J; Treadway J; Green J; Koshman YE; Zafiratos M; Mittelstadt S; Blomme E; Foley CM (Toxicological sciences : an official journal of the Society of Toxicology, 2025)