Nano-carrier, design, synthesis, in silico ADMET, anti-proliferative assessments and docking of [1,2,4]triazolo[4,3-a]quinoxalines as Topo-II inhibitors and DNA intercalators.
Saved in:
| Title: | Nano-carrier, design, synthesis, in silico ADMET, anti-proliferative assessments and docking of [1,2,4]triazolo[4,3-a]quinoxalines as Topo-II inhibitors and DNA intercalators. |
|---|---|
| Authors: | Aljohani AKB; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Almadani SA; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Alsulaimany M; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Aljuhani N; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Samman WA; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Al-Shareef AH; Department of Chemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia., Alghamdi R; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia., Tayeb SM; Department of Pharmaceutical Science, College of Pharmacy, Umm Al-Qura University, 24381, Makkah, Saudi Arabia., Alharbi HY; Department of Chemistry, Faculty of Science, Taibah University, Yanbu, Saudi Arabia., Aljohani MS; Department of Chemistry, Faculty of Science, Taibah University, Yanbu, Saudi Arabia., El-Adl K; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt. eladlkhaled74@azhar.edu.eg.; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, 11884, Cairo, Egypt. eladlkhaled74@azhar.edu.eg., Salem M; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University-Arish Branch, Arish, Egypt. |
| Source: | Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2025 Sep; Vol. 398 (9), pp. 12727-12743. Date of Electronic Publication: 2025 Apr 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40214726 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Nano-carrier, design, synthesis, in silico ADMET, anti-proliferative assessments and docking of [1,2,4]triazolo[4,3-a]quinoxalines as Topo-II inhibitors and DNA intercalators. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Aljohani+AKB%22">Aljohani AKB</searchLink>; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Almadani+SA%22">Almadani SA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alsulaimany+M%22">Alsulaimany M</searchLink>; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aljuhani+N%22">Aljuhani N</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Samman+WA%22">Samman WA</searchLink>; Department of Pharmacology and Toxicology, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Shareef+AH%22">Al-Shareef AH</searchLink>; Department of Chemistry, College of Science, University of Jeddah, Jeddah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alghamdi+R%22">Alghamdi R</searchLink>; Department of Pharmacognosy and Pharmaceutical Chemistry, College of Pharmacy, Taibah University, 42353, Medina, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Tayeb+SM%22">Tayeb SM</searchLink>; Department of Pharmaceutical Science, College of Pharmacy, Umm Al-Qura University, 24381, Makkah, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alharbi+HY%22">Alharbi HY</searchLink>; Department of Chemistry, Faculty of Science, Taibah University, Yanbu, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Aljohani+MS%22">Aljohani MS</searchLink>; Department of Chemistry, Faculty of Science, Taibah University, Yanbu, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22El-Adl+K%22">El-Adl K</searchLink>; Pharmaceutical Chemistry Department, Faculty of Pharmacy, Heliopolis University for Sustainable Development, Cairo, Egypt. eladlkhaled74@azhar.edu.eg.; Pharmaceutical Medicinal Chemistry and Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City, 11884, Cairo, Egypt. eladlkhaled74@azhar.edu.eg.<br /><searchLink fieldCode="AU" term="%22Salem+M%22">Salem M</searchLink>; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sinai University-Arish Branch, Arish, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220326264%22">Naunyn-Schmiedeberg's archives of pharmacology</searchLink> [Naunyn Schmiedebergs Arch Pharmacol] 2025 Sep; Vol. 398 (9), pp. 12727-12743. <i>Date of Electronic Publication: </i>2025 Apr 11. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0326264 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-1912 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200281298%22">00281298 </searchLink><i>NLM ISO Abbreviation: </i>Naunyn Schmiedebergs Arch Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40214726 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00210-025-04052-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 12727 Titles: – TitleFull: Nano-carrier, design, synthesis, in silico ADMET, anti-proliferative assessments and docking of [1,2,4]triazolo[4,3-a]quinoxalines as Topo-II inhibitors and DNA intercalators. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Aljohani AKB – PersonEntity: Name: NameFull: Almadani SA – PersonEntity: Name: NameFull: Alsulaimany M – PersonEntity: Name: NameFull: Aljuhani N – PersonEntity: Name: NameFull: Samman WA – PersonEntity: Name: NameFull: Al-Shareef AH – PersonEntity: Name: NameFull: Alghamdi R – PersonEntity: Name: NameFull: Tayeb SM – PersonEntity: Name: NameFull: Alharbi HY – PersonEntity: Name: NameFull: Aljohani MS – PersonEntity: Name: NameFull: El-Adl K – PersonEntity: Name: NameFull: Salem M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2025 Sep Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1432-1912 Numbering: – Type: volume Value: 398 – Type: issue Value: 9 Titles: – TitleFull: Naunyn-Schmiedeberg's archives of pharmacology Type: main |
| ResultId | 1 |
