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A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.

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Title: A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.
Authors: Gopalakrishnan V; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA., Kumar C; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Robertsen I; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway., Morehouse C; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA., Sparklin B; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA., Khader S; Data Science and Artificial Intelligence, Biopharmaceuticals R&D, AstraZeneca, USA., Henry I; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Johnson LK; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway., Hertel JK; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway., Christensen H; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway., Sandbu R; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway., Greasley PJ; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Sellman BR; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA., Åsberg A; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway; Department of Transplantation Medicine, Oslo University Hospital, P.O.Box 4950 Nydalen, 0424 Oslo, Norway., Andersson S; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Löfmark RJ; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Hjelmesæth J; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Institute of Clinical Medicine, University of Oslo, P.O. Box 1171, 0318 Oslo, Norway., Karlsson C; Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Cohen TS; Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.
Source: Mucosal immunology [Mucosal Immunol] 2025 Aug; Vol. 18 (4), pp. 825-835. Date of Electronic Publication: 2025 Apr 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE
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  Data: A multi-omics microbiome signature is associated with the benefits of gastric bypass surgery and is differentiated from diet induced weight loss through 2 years of follow-up.
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  Data: <searchLink fieldCode="AU" term="%22Gopalakrishnan+V%22">Gopalakrishnan V</searchLink>; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.<br /><searchLink fieldCode="AU" term="%22Kumar+C%22">Kumar C</searchLink>; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Robertsen+I%22">Robertsen I</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Morehouse+C%22">Morehouse C</searchLink>; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.<br /><searchLink fieldCode="AU" term="%22Sparklin+B%22">Sparklin B</searchLink>; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.<br /><searchLink fieldCode="AU" term="%22Khader+S%22">Khader S</searchLink>; Data Science and Artificial Intelligence, Biopharmaceuticals R&D, AstraZeneca, USA.<br /><searchLink fieldCode="AU" term="%22Henry+I%22">Henry I</searchLink>; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Johnson+LK%22">Johnson LK</searchLink>; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway.<br /><searchLink fieldCode="AU" term="%22Hertel+JK%22">Hertel JK</searchLink>; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway.<br /><searchLink fieldCode="AU" term="%22Christensen+H%22">Christensen H</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Sandbu+R%22">Sandbu R</searchLink>; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway.<br /><searchLink fieldCode="AU" term="%22Greasley+PJ%22">Greasley PJ</searchLink>; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Sellman+BR%22">Sellman BR</searchLink>; Early Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.<br /><searchLink fieldCode="AU" term="%22Åsberg+A%22">Åsberg A</searchLink>; Section for Pharmacology and Pharmaceutical Biosciences, Department of Pharmacy, University of Oslo, PO 1068 Blindern, 0316 Oslo, Norway; Department of Transplantation Medicine, Oslo University Hospital, P.O.Box 4950 Nydalen, 0424 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Andersson+S%22">Andersson S</searchLink>; Oligonucleotide Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Löfmark+RJ%22">Löfmark RJ</searchLink>; Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Hjelmesæth+J%22">Hjelmesæth J</searchLink>; Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust, P.O.Box 2168, 3103 Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine, Institute of Clinical Medicine, University of Oslo, P.O. Box 1171, 0318 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Karlsson+C%22">Karlsson C</searchLink>; Late-stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden; Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Cohen+TS%22">Cohen TS</searchLink>; Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, USA.
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  Data: <searchLink fieldCode="JN" term="%22101299742%22">Mucosal immunology</searchLink> [Mucosal Immunol] 2025 Aug; Vol. 18 (4), pp. 825-835. <i>Date of Electronic Publication: </i>2025 Apr 11.
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