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Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.

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Title: Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
Authors: Tandon R; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Center for Machine Learning, Georgia Institute of Technology, Atlanta, GA 30332, USA., Zhao L; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA., Watson CM; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Sarkar N; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA., Elmor M; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Heilman C; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Sanders K; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Hales CM; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA., Yang H; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA., Loring DW; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Goldstein FC; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA., Hanfelt JJ; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA., Duong DM; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA., Johnson ECB; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA., Wingo AP; Department of Psychiatry, Emory School of Medicine, Atlanta, GA 30322, USA.; Division of Mental Health, Atlanta VA Medical Center, Atlanta, GA 30033, USA., Wingo TS; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA., Roberts BR; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA., Seyfried NT; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA., Levey AI; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA., Lah JJ; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA., Mitchell CS; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Center for Machine Learning, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Source: Brain communications [Brain Commun] 2025 Mar 25; Vol. 7 (2), pp. fcaf121. Date of Electronic Publication: 2025 Mar 25 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
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  Data: Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
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  Data: <searchLink fieldCode="AU" term="%22Tandon+R%22">Tandon R</searchLink>; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Center for Machine Learning, Georgia Institute of Technology, Atlanta, GA 30332, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.<br /><searchLink fieldCode="AU" term="%22Watson+CM%22">Watson CM</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+N%22">Sarkar N</searchLink>; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.<br /><searchLink fieldCode="AU" term="%22Elmor+M%22">Elmor M</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Heilman+C%22">Heilman C</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Sanders+K%22">Sanders K</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Hales+CM%22">Hales CM</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.<br /><searchLink fieldCode="AU" term="%22Loring+DW%22">Loring DW</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Goldstein+FC%22">Goldstein FC</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Hanfelt+JJ%22">Hanfelt JJ</searchLink>; Department of Biostatistics and Bioinformatics, Emory School of Public Health, Atlanta, GA 30322, USA.; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.<br /><searchLink fieldCode="AU" term="%22Duong+DM%22">Duong DM</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+ECB%22">Johnson ECB</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Wingo+AP%22">Wingo AP</searchLink>; Department of Psychiatry, Emory School of Medicine, Atlanta, GA 30322, USA.; Division of Mental Health, Atlanta VA Medical Center, Atlanta, GA 30033, USA.<br /><searchLink fieldCode="AU" term="%22Wingo+TS%22">Wingo TS</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Roberts+BR%22">Roberts BR</searchLink>; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Seyfried+NT%22">Seyfried NT</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Levey+AI%22">Levey AI</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Lah+JJ%22">Lah JJ</searchLink>; Emory Goizueta Alzheimer's Disease Research Center, Atlanta, GA 30329, USA.; Department of Neurology, Emory School of Medicine, Atlanta, GA 30322, USA.; Center for Neurodegenerative Disease, Emory University, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Mitchell+CS%22">Mitchell CS</searchLink>; Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.; Center for Machine Learning, Georgia Institute of Technology, Atlanta, GA 30332, USA.
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  Data: <searchLink fieldCode="JN" term="%22101755125%22">Brain communications</searchLink> [Brain Commun] 2025 Mar 25; Vol. 7 (2), pp. fcaf121. <i>Date of Electronic Publication: </i>2025 Mar 25 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101755125 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2632-1297 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226321297%22">26321297 </searchLink><i>NLM ISO Abbreviation: </i>Brain Commun <i>Subsets: </i>PubMed not MEDLINE
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