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Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development.

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Title: Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development.
Authors: Vicenzi S; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Gao F; Center for Translational Vision Research, Departments of Physiology and Biophysics and Department of Ophthalmology, University of California, Irvine, CA, 92617, USA., Côté P; Department of Pediatrics, University of California San Diego, La Jolla, CA, 92037, USA., Hartman JD; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Avsharian LC; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Vora AA; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA., Rowe RG; Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, and Harvard Medical School, Boston, MA, 02115, USA., Li H; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.; Department of Pediatrics, University of California San Diego, La Jolla, CA, 92037, USA.; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, 92123, USA., Skowronska-Krawczyk D; Center for Translational Vision Research, Departments of Physiology and Biophysics and Department of Ophthalmology, University of California, Irvine, CA, 92617, USA. dorotask@hs.uci.edu., Crews LA; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.; Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.
Source: GeroScience [Geroscience] 2025 Aug; Vol. 47 (4), pp. 5449-5467. Date of Electronic Publication: 2025 Apr 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Systemic deficits in lipid homeostasis promote aging-associated impairments in B cell progenitor development.
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  Data: <searchLink fieldCode="AU" term="%22Vicenzi+S%22">Vicenzi S</searchLink>; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Gao+F%22">Gao F</searchLink>; Center for Translational Vision Research, Departments of Physiology and Biophysics and Department of Ophthalmology, University of California, Irvine, CA, 92617, USA.<br /><searchLink fieldCode="AU" term="%22Côté+P%22">Côté P</searchLink>; Department of Pediatrics, University of California San Diego, La Jolla, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Hartman+JD%22">Hartman JD</searchLink>; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Avsharian+LC%22">Avsharian LC</searchLink>; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Vora+AA%22">Vora AA</searchLink>; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.<br /><searchLink fieldCode="AU" term="%22Rowe+RG%22">Rowe RG</searchLink>; Boston Children's Hospital, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, and Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA.; Department of Pediatrics, University of California San Diego, La Jolla, CA, 92037, USA.; Division of Hematology/Oncology, Rady Children's Hospital, San Diego, CA, 92123, USA.<br /><searchLink fieldCode="AU" term="%22Skowronska-Krawczyk+D%22">Skowronska-Krawczyk D</searchLink>; Center for Translational Vision Research, Departments of Physiology and Biophysics and Department of Ophthalmology, University of California, Irvine, CA, 92617, USA. dorotask@hs.uci.edu.<br /><searchLink fieldCode="AU" term="%22Crews+LA%22">Crews LA</searchLink>; Division of Regenerative Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.; Moores Cancer Center, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.; Sanford Stem Cell Institute, University of California San Diego, La Jolla, CA, 92037, USA. lcrews@ucsd.edu.
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              Text: 2025 Aug
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