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Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of the Muscarinic M 1 Positive Allosteric Modulator VU0467319 for Alzheimer's disease: A Single Ascending-Dose Study in Healthy Participants.

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Title: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of the Muscarinic M 1 Positive Allosteric Modulator VU0467319 for Alzheimer's disease: A Single Ascending-Dose Study in Healthy Participants.
Authors: Conley AC, Key AP, Blackford JU, Russell JK, Albert KM, Gong X, Bubser M, Rook JM, Conn PJ, Lindsley CW, Jones CK, Newhouse PA
Source: Research square [Res Sq] 2025 Apr 04. Date of Electronic Publication: 2025 Apr 04.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40235479
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of the Muscarinic M 1 Positive Allosteric Modulator VU0467319 for Alzheimer's disease: A Single Ascending-Dose Study in Healthy Participants.
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  Data: <searchLink fieldCode="JN" term="%22101768035%22">Research square</searchLink> [Res Sq] 2025 Apr 04. <i>Date of Electronic Publication: </i>2025 Apr 04.
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  Data: <i>Country of Publication: </i>United States <i>NLM ID: </i>101768035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2693-5015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226935015%22">26935015 </searchLink><i>NLM ISO Abbreviation: </i>Res Sq <i>Subsets: </i>PubMed not MEDLINE
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      – Type: doi
        Value: 10.21203/rs.3.rs-6271510/v1
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      – Code: eng
        Text: English
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      – TitleFull: Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Effects of the Muscarinic M 1 Positive Allosteric Modulator VU0467319 for Alzheimer's disease: A Single Ascending-Dose Study in Healthy Participants.
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            NameFull: Conley AC
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            NameFull: Key AP
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            NameFull: Russell JK
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          Dates:
            – D: 04
              M: 04
              Text: 2025 Apr 04
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2693-5015
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