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Current Limitations of Electronic Health Record Systems in Supporting Pragmatic Clinical Trials: Insights from the eMERGE Consortium.

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Title: Current Limitations of Electronic Health Record Systems in Supporting Pragmatic Clinical Trials: Insights from the eMERGE Consortium.
Authors: Wagholikar KB; Massachusetts General Hospital., Pacheco JA; Northwestern University Feinberg School of Medicine., Gordon AS; Center for Genetic Medicine, Northwestern University., Khan A; Vagelos College of Physicians & Surgeons, Columbia University., Khales BN; Cincinnati Children's Hospital Medical Center., Benoit B; Mass General Brigham Inc., Kerman BJ; Brigham and Women's Hospital and Harvard Medical School., Weng C; Columbia University Irving Medical Center., Ta C; Columbia University., Prows CA; Children's Hospital Medical Center., Johnson R; The University of Alabama at Birmingham., Roden DM; Vanderbilt University School of Medicine., Crosslin D; University of Washington., McNally EM; Northwestern University., Karlson EW; Brigham and Women's Hospital Department of Medicine., Mentch F; The Children's Hospital of Philadelphia Center for Applied Genomics., Jarvik GP; University of Washington Medical Center., Wiesner GL; Vanderbilt University., Hakonarson H; Perelman School of Medicine of the University of Pennsylvania., Cimino JJ; University of Alabama-Birmingham., Thayer JG; Children's Hospital of Philadelphia., Smoller JW; Massachusetts General Hospital., Linder JE; Vanderbilt University Medical Center., Connolly J; The Children's Hospital of Philadelphia Center for Applied Genomics., Peterson JF; Vanderbilt University Medical Center., Cortopassi J; University of Alabama at Birmingham Health System Authority., Kiryluk K; Columbia University., Hamed M; Mayo Foundation for Medical Education and Research., Maradik M; Northwestern University Feinberg School of Medicine., Puckelwartz MJ; Northwestern University., Naderian M; Mayo Clinic, Rochester, MN., Walton N; National Institutes of Health., Limdi N; The University of Alabama at Birmingham., Maripuri DP; Children's Hospital of Philadelphia., Walunas T; Northwestern University., Gainer V; Mass General Brigham Inc., Luo Y; Northwestern University Feinberg School of Medicine., Liu C; Boston Children's Hospital., Kenny EE; Icahn School of Medicine at Mount Sinai., Espinoza A; Northwestern University Feinberg School of Medicine., Rowley R; National Institutes of Health., Wei WQ; Vanderbilt University Medical Center., Murphy SN; Mass General Brigham Inc.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Apr 03. Date of Electronic Publication: 2025 Apr 03.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Wagholikar+KB%22">Wagholikar KB</searchLink>; Massachusetts General Hospital.<br /><searchLink fieldCode="AU" term="%22Pacheco+JA%22">Pacheco JA</searchLink>; Northwestern University Feinberg School of Medicine.<br /><searchLink fieldCode="AU" term="%22Gordon+AS%22">Gordon AS</searchLink>; Center for Genetic Medicine, Northwestern University.<br /><searchLink fieldCode="AU" term="%22Khan+A%22">Khan A</searchLink>; Vagelos College of Physicians & Surgeons, Columbia University.<br /><searchLink fieldCode="AU" term="%22Khales+BN%22">Khales BN</searchLink>; Cincinnati Children's Hospital Medical Center.<br /><searchLink fieldCode="AU" term="%22Benoit+B%22">Benoit B</searchLink>; Mass General Brigham Inc.<br /><searchLink fieldCode="AU" term="%22Kerman+BJ%22">Kerman BJ</searchLink>; Brigham and Women's Hospital and Harvard Medical School.<br /><searchLink fieldCode="AU" term="%22Weng+C%22">Weng C</searchLink>; Columbia University Irving Medical Center.<br /><searchLink fieldCode="AU" term="%22Ta+C%22">Ta C</searchLink>; Columbia University.<br /><searchLink fieldCode="AU" term="%22Prows+CA%22">Prows CA</searchLink>; Children's Hospital Medical Center.<br /><searchLink fieldCode="AU" term="%22Johnson+R%22">Johnson R</searchLink>; The University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; Vanderbilt University School of Medicine.<br /><searchLink fieldCode="AU" term="%22Crosslin+D%22">Crosslin D</searchLink>; University of Washington.<br /><searchLink fieldCode="AU" term="%22McNally+EM%22">McNally EM</searchLink>; Northwestern University.<br /><searchLink fieldCode="AU" term="%22Karlson+EW%22">Karlson EW</searchLink>; Brigham and Women's Hospital Department of Medicine.<br /><searchLink fieldCode="AU" term="%22Mentch+F%22">Mentch F</searchLink>; The Children's Hospital of Philadelphia Center for Applied Genomics.<br /><searchLink fieldCode="AU" term="%22Jarvik+GP%22">Jarvik GP</searchLink>; University of Washington Medical Center.<br /><searchLink fieldCode="AU" term="%22Wiesner+GL%22">Wiesner GL</searchLink>; Vanderbilt University.<br /><searchLink fieldCode="AU" term="%22Hakonarson+H%22">Hakonarson H</searchLink>; Perelman School of Medicine of the University of Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Cimino+JJ%22">Cimino JJ</searchLink>; University of Alabama-Birmingham.<br /><searchLink fieldCode="AU" term="%22Thayer+JG%22">Thayer JG</searchLink>; Children's Hospital of Philadelphia.<br /><searchLink fieldCode="AU" term="%22Smoller+JW%22">Smoller JW</searchLink>; Massachusetts General Hospital.<br /><searchLink fieldCode="AU" term="%22Linder+JE%22">Linder JE</searchLink>; Vanderbilt University Medical Center.<br /><searchLink fieldCode="AU" term="%22Connolly+J%22">Connolly J</searchLink>; The Children's Hospital of Philadelphia Center for Applied Genomics.<br /><searchLink fieldCode="AU" term="%22Peterson+JF%22">Peterson JF</searchLink>; Vanderbilt University Medical Center.<br /><searchLink fieldCode="AU" term="%22Cortopassi+J%22">Cortopassi J</searchLink>; University of Alabama at Birmingham Health System Authority.<br /><searchLink fieldCode="AU" term="%22Kiryluk+K%22">Kiryluk K</searchLink>; Columbia University.<br /><searchLink fieldCode="AU" term="%22Hamed+M%22">Hamed M</searchLink>; Mayo Foundation for Medical Education and Research.<br /><searchLink fieldCode="AU" term="%22Maradik+M%22">Maradik M</searchLink>; Northwestern University Feinberg School of Medicine.<br /><searchLink fieldCode="AU" term="%22Puckelwartz+MJ%22">Puckelwartz MJ</searchLink>; Northwestern University.<br /><searchLink fieldCode="AU" term="%22Naderian+M%22">Naderian M</searchLink>; Mayo Clinic, Rochester, MN.<br /><searchLink fieldCode="AU" term="%22Walton+N%22">Walton N</searchLink>; National Institutes of Health.<br /><searchLink fieldCode="AU" term="%22Limdi+N%22">Limdi N</searchLink>; The University of Alabama at Birmingham.<br /><searchLink fieldCode="AU" term="%22Maripuri+DP%22">Maripuri DP</searchLink>; Children's Hospital of Philadelphia.<br /><searchLink fieldCode="AU" term="%22Walunas+T%22">Walunas T</searchLink>; Northwestern University.<br /><searchLink fieldCode="AU" term="%22Gainer+V%22">Gainer V</searchLink>; Mass General Brigham Inc.<br /><searchLink fieldCode="AU" term="%22Luo+Y%22">Luo Y</searchLink>; Northwestern University Feinberg School of Medicine.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Boston Children's Hospital.<br /><searchLink fieldCode="AU" term="%22Kenny+EE%22">Kenny EE</searchLink>; Icahn School of Medicine at Mount Sinai.<br /><searchLink fieldCode="AU" term="%22Espinoza+A%22">Espinoza A</searchLink>; Northwestern University Feinberg School of Medicine.<br /><searchLink fieldCode="AU" term="%22Rowley+R%22">Rowley R</searchLink>; National Institutes of Health.<br /><searchLink fieldCode="AU" term="%22Wei+WQ%22">Wei WQ</searchLink>; Vanderbilt University Medical Center.<br /><searchLink fieldCode="AU" term="%22Murphy+SN%22">Murphy SN</searchLink>; Mass General Brigham Inc.
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