View in EDS

Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M2 Muscarinic Acetylcholine Receptor.

Saved in:
Bibliographic Details
Title: Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M2 Muscarinic Acetylcholine Receptor.
Authors: Szabó R; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary., Szepesi Kovács D; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary., Kiss DJ; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary., Yazdi ZN; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary., Tóth AD; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Internal Medicine and Haematology, Semmelweis University, H-1088 Budapest, Hungary., Brea J; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain., Loza MI; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain., Meszéna D; Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary., Wittner L; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary., Ulbert I; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Neurosurgery and Neurointervention, Semmelweis University, H-1145 Budapest, Hungary.; Department of Information Technology and Bionics, Péter Pázmány Catholic University, H-1083 Budapest, Hungary., Volk B; Directorate of Drug Substance Development, Egis Pharmaceuticals Plc., P.O. Box 100, H-1475 Budapest, Hungary., Hunyady L; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Physiology, Faculty of Medicine, Semmelweis University, H-1094 Budapest, Hungary., Keserű GM; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.
Source: ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Mar 20; Vol. 16 (4), pp. 552-559. Date of Electronic Publication: 2025 Mar 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40236555
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M<subscript>2</subscript> Muscarinic Acetylcholine Receptor.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Szabó+R%22">Szabó R</searchLink>; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Szepesi+Kovács+D%22">Szepesi Kovács D</searchLink>; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Kiss+DJ%22">Kiss DJ</searchLink>; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Yazdi+ZN%22">Yazdi ZN</searchLink>; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Tóth+AD%22">Tóth AD</searchLink>; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Internal Medicine and Haematology, Semmelweis University, H-1088 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Brea+J%22">Brea J</searchLink>; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Loza+MI%22">Loza MI</searchLink>; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy, and Pharmaceutical Technology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Meszéna+D%22">Meszéna D</searchLink>; Department of Neurology, Center for Neurotechnology and Neurorecovery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, United States.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Wittner+L%22">Wittner L</searchLink>; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Ulbert+I%22">Ulbert I</searchLink>; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.; Integrative Neuroscience Research Group, Institute of Cognitive Neuroscience and Psychology, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Neurosurgery and Neurointervention, Semmelweis University, H-1145 Budapest, Hungary.; Department of Information Technology and Bionics, Péter Pázmány Catholic University, H-1083 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Volk+B%22">Volk B</searchLink>; Directorate of Drug Substance Development, Egis Pharmaceuticals Plc., P.O. Box 100, H-1475 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Hunyady+L%22">Hunyady L</searchLink>; Institute of Molecular Life Sciences, Centre of Excellence of the Hungarian Academy of Sciences, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Physiology, Faculty of Medicine, Semmelweis University, H-1094 Budapest, Hungary.<br /><searchLink fieldCode="AU" term="%22Keserű+GM%22">Keserű GM</searchLink>; Medicinal Chemistry Research Group, HUN-REN Research Centre for Natural Sciences, H-1117 Budapest, Hungary.; Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, H-1111 Budapest, Hungary.; National Laboratory for Drug Research and Development, H-1117 Budapest, Hungary.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101521073%22">ACS medicinal chemistry letters</searchLink> [ACS Med Chem Lett] 2025 Mar 20; Vol. 16 (4), pp. 552-559. <i>Date of Electronic Publication: </i>2025 Mar 20 (<i>Print Publication: </i>2025).
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101521073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>1948-5875 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219485875%22">19485875 </searchLink><i>NLM ISO Abbreviation: </i>ACS Med Chem Lett <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40236555
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1021/acsmedchemlett.4c00592
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 552
    Titles:
      – TitleFull: Design, Synthesis, and Evaluation of a New Fluorescent Ligand for the M2 Muscarinic Acetylcholine Receptor.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Szabó R
      – PersonEntity:
          Name:
            NameFull: Szepesi Kovács D
      – PersonEntity:
          Name:
            NameFull: Kiss DJ
      – PersonEntity:
          Name:
            NameFull: Yazdi ZN
      – PersonEntity:
          Name:
            NameFull: Tóth AD
      – PersonEntity:
          Name:
            NameFull: Brea J
      – PersonEntity:
          Name:
            NameFull: Loza MI
      – PersonEntity:
          Name:
            NameFull: Meszéna D
      – PersonEntity:
          Name:
            NameFull: Wittner L
      – PersonEntity:
          Name:
            NameFull: Ulbert I
      – PersonEntity:
          Name:
            NameFull: Volk B
      – PersonEntity:
          Name:
            NameFull: Hunyady L
      – PersonEntity:
          Name:
            NameFull: Keserű GM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 20
              M: 03
              Text: 2025 Mar 20
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-print
              Value: 1948-5875
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 4
          Titles:
            – TitleFull: ACS medicinal chemistry letters
              Type: main
ResultId 1