Perspectives on cancer therapy-synthetic lethal precision medicine strategies, molecular mechanisms, therapeutic targets and current technical challenges.

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Title: Perspectives on cancer therapy-synthetic lethal precision medicine strategies, molecular mechanisms, therapeutic targets and current technical challenges.
Authors: Peng S; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China., Long M; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China., Chen Q; Department of Anesthesiology, The First People's Hospital of Chenzhou, The Chenzhou Affiliated Hospital, Hengyang Medical School, University of South China, Chenzhou, Hunan, 423000, China., Yin Z; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China., Zeng C; Department of Pathology, Yueyang Central Hospital, Yueyang, China., Zhang W; Department of Pathology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, 437100, Hubei, China., Wen Q; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China., Zhang X; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China., Ke W; Department of Anesthesiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, China. wqke2@stu.edu.cn., Wu Y; Department of Pathology, Xiangtan Center Hospital, Xiangtan City, Hunan province, 411100, China. 1345270430@qq.com.; Department of Pathology, The Affiliated Hospital of Hunan University, Xiangtan City, Hunan Province, China. 1345270430@qq.com.
Source: Cell death discovery [Cell Death Discov] 2025 Apr 16; Vol. 11 (1), pp. 179. Date of Electronic Publication: 2025 Apr 16.
Publication Type: Journal Article; Review
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Perspectives on cancer therapy-synthetic lethal precision medicine strategies, molecular mechanisms, therapeutic targets and current technical challenges.
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  Data: <searchLink fieldCode="AU" term="%22Peng+S%22">Peng S</searchLink>; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China.<br /><searchLink fieldCode="AU" term="%22Long+M%22">Long M</searchLink>; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Department of Anesthesiology, The First People's Hospital of Chenzhou, The Chenzhou Affiliated Hospital, Hengyang Medical School, University of South China, Chenzhou, Hunan, 423000, China.<br /><searchLink fieldCode="AU" term="%22Yin+Z%22">Yin Z</searchLink>; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China.<br /><searchLink fieldCode="AU" term="%22Zeng+C%22">Zeng C</searchLink>; Department of Pathology, Yueyang Central Hospital, Yueyang, China.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Department of Pathology, Xianning Central Hospital, The First Affiliated Hospital of Hubei University of Science and Technology, Xianning, 437100, Hubei, China.<br /><searchLink fieldCode="AU" term="%22Wen+Q%22">Wen Q</searchLink>; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Oncology, Graduate Collaborative Training Base of The First People's Hospital of Xiangtan City, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, China.; Department of Oncology, The First People's Hospital of Xiangtan City, Xiangtan, Hunan, 411101, China.<br /><searchLink fieldCode="AU" term="%22Ke+W%22">Ke W</searchLink>; Department of Anesthesiology, The First Affiliated Hospital of Shantou University Medical College, Shantou, Guangdong Province, China. wqke2@stu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Pathology, Xiangtan Center Hospital, Xiangtan City, Hunan province, 411100, China. 1345270430@qq.com.; Department of Pathology, The Affiliated Hospital of Hunan University, Xiangtan City, Hunan Province, China. 1345270430@qq.com.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 Apr 16; Vol. 11 (1), pp. 179. <i>Date of Electronic Publication: </i>2025 Apr 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41420-025-02418-8
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              Text: 2025 Apr 16
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