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Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses.

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Title: Epigenetic and genetic profiling of comorbidity patterns among substance dependence diagnoses.
Authors: Pathak GA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Pietrzak RH; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA., Lacobelle A; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Overstreet C; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Wendt FR; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Deak JD; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Friligkou E; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Nunez YZ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Montalvo-Ortiz JL; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Levey DF; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Kranzler HR; Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine and the Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA., Gelernter J; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA., Polimanti R; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. renato.polimanti@yale.edu.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA. renato.polimanti@yale.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2025 Sep; Vol. 30 (9), pp. 4435-4443. Date of Electronic Publication: 2025 Apr 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Pathak+GA%22">Pathak GA</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Pietrzak+RH%22">Pietrzak RH</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.; Department of Social and Behavioral Sciences, Yale School of Public Health, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Lacobelle+A%22">Lacobelle A</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Overstreet+C%22">Overstreet C</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Wendt+FR%22">Wendt FR</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA.<br /><searchLink fieldCode="AU" term="%22Deak+JD%22">Deak JD</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Friligkou+E%22">Friligkou E</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Nunez+YZ%22">Nunez YZ</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Montalvo-Ortiz+JL%22">Montalvo-Ortiz JL</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Levey+DF%22">Levey DF</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Kranzler+HR%22">Kranzler HR</searchLink>; Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine and the Mental Illness Research, Education and Clinical Center, Crescenz VAMC, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gelernter+J%22">Gelernter J</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Polimanti+R%22">Polimanti R</searchLink>; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA. renato.polimanti@yale.edu.; U.S Department of Veteran Affairs Connecticut Healthcare System, West Haven, CT, USA. renato.polimanti@yale.edu.
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