Intranasal spike and nucleoprotein fusion protein-based vaccine provides cross-protection and reduced transmission against SARS-CoV-2 variants. - Lakhrif Z; Poupée-Beaugé A; Boursin F; Ducournau C; Lantier L; Moiré N; Carpentier R; Rossignol C; Maquart M; Jospin F; Merat L; Caul-Futy M; et al. (NPJ vaccines, 2025)