Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma.

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Title: Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma.
Authors: Yao GS; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Dai JS; Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China.; Department of Obstetrics and Gynecology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Fu LM; Department of Urology, The Second Xiangya Hospital of Central South University, Changsha, Hunan, China.; Uro-Oncology Institute of Central South University, Changsha, Hunan, China., Lin J; Department of Pediatrics, The Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China., Tan ZP; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Dai L; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Chen W; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Luo JH; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China.; Institute of Precision Medicine, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China., Wei JH; Department of Urology, Sun Yat-Sen University First Affiliated Hospital, Guangzhou, Guangdong, China.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Apr 04; Vol. 16, pp. 1470145. Date of Electronic Publication: 2025 Apr 04 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:1663-9812
DOI:10.3389/fphar.2025.1470145