A network pharmacological target mendelian randomization study on the neuroprotective effects of active ingredients in mahuang fuzi xixin decoction for multiple sclerosis.

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Title: A network pharmacological target mendelian randomization study on the neuroprotective effects of active ingredients in mahuang fuzi xixin decoction for multiple sclerosis.
Authors: Li WJ; Department of Neurosurgery, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou510000, China., Feng CL; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China., Nie ZY; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China., Li LY; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China., Guo JH; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China., Liu XY; Third Clinical Medical School, Guangzhou Medical University, Guangzhou510150, China., Su YH; Third Clinical Medical School, Guangzhou Medical University, Guangzhou510150, China., Liu SS; Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou510623, China., Cui ZZ; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.
Source: Journal of Asian natural products research [J Asian Nat Prod Res] 2026 Jan; Vol. 28 (1), pp. 91-111. Date of Electronic Publication: 2025 Apr 21.
Publication Type: Journal Article
Journal Info: Publisher: Informa Healthcare Country of Publication: England NLM ID: 100888334 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-2213 (Electronic) Linking ISSN: 10286020 NLM ISO Abbreviation: J Asian Nat Prod Res Subsets: MEDLINE
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  Data: A network pharmacological target mendelian randomization study on the neuroprotective effects of active ingredients in mahuang fuzi xixin decoction for multiple sclerosis.
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  Data: <searchLink fieldCode="AU" term="%22Li+WJ%22">Li WJ</searchLink>; Department of Neurosurgery, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou510000, China.<br /><searchLink fieldCode="AU" term="%22Feng+CL%22">Feng CL</searchLink>; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.<br /><searchLink fieldCode="AU" term="%22Nie+ZY%22">Nie ZY</searchLink>; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.<br /><searchLink fieldCode="AU" term="%22Li+LY%22">Li LY</searchLink>; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.<br /><searchLink fieldCode="AU" term="%22Guo+JH%22">Guo JH</searchLink>; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.<br /><searchLink fieldCode="AU" term="%22Liu+XY%22">Liu XY</searchLink>; Third Clinical Medical School, Guangzhou Medical University, Guangzhou510150, China.<br /><searchLink fieldCode="AU" term="%22Su+YH%22">Su YH</searchLink>; Third Clinical Medical School, Guangzhou Medical University, Guangzhou510150, China.<br /><searchLink fieldCode="AU" term="%22Liu+SS%22">Liu SS</searchLink>; Department of Hematology and Oncology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangdong Provincial Clinical Research Center for Child Health, Guangzhou510623, China.<br /><searchLink fieldCode="AU" term="%22Cui+ZZ%22">Cui ZZ</searchLink>; Department of Traditional Chinese Medicine, Guangdong Provincial Key Laboratory of Major Obstetric Diseases, Guangdong Provincial Clinical Research Center for Obstetries and Gynecology, The Third Affiliated Hospital, Guangzhou Medical University, Guangzhou510000, China.
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  Data: <searchLink fieldCode="JN" term="%22100888334%22">Journal of Asian natural products research</searchLink> [J Asian Nat Prod Res] 2026 Jan; Vol. 28 (1), pp. 91-111. <i>Date of Electronic Publication: </i>2025 Apr 21.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Informa+Healthcare%22">Informa Healthcare </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100888334 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1477-2213 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210286020%22">10286020 </searchLink><i>NLM ISO Abbreviation: </i>J Asian Nat Prod Res <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40257326
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/10286020.2025.2491612
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      – Code: eng
        Text: English
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            – D: 01
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              Text: 2026 Jan
              Type: published
              Y: 2026
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