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A small molecule PKCε inhibitor reduces hyperalgesia induced by paclitaxel or opioid withdrawal.

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Title: A small molecule PKCε inhibitor reduces hyperalgesia induced by paclitaxel or opioid withdrawal.
Authors: Gregory-Flores A; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA., Bonet IJ; Department of Oral and Maxillofacial Surgery, UCSF Pain and Addiction Research Center, and.; Department of Medicine, Division of Neuroscience, UCSF, San Francisco, California, USA., Desaivre S; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA., Levine JD; Department of Oral and Maxillofacial Surgery, UCSF Pain and Addiction Research Center, and.; Department of Medicine, Division of Neuroscience, UCSF, San Francisco, California, USA., McHardy SF; Department of Chemistry, Center for Innovative Drug Discovery, and., de Kraker HC; Department of Chemistry, Center for Innovative Drug Discovery, and., Clanton NA; Voelcker Preclinical Pharmacology Core, Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA., LoCoco PM; Voelcker Preclinical Pharmacology Core, Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA., Russell NM; Division of Pharmacology and Toxicology, College of Pharmacy., Fleischer C; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA., Messing RO; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.; Division of Pharmacology and Toxicology, College of Pharmacy.; Department of Neurology and the Mulva Clinic for the Neurosciences, Dell Medical School, and., Marinelli M; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.; Division of Pharmacology and Toxicology, College of Pharmacy.; Department of Neurology and the Mulva Clinic for the Neurosciences, Dell Medical School, and.; Department of Psychiatry and Behavioral Sciences, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
Source: JCI insight [JCI Insight] 2025 Apr 22; Vol. 10 (8). Date of Electronic Publication: 2025 Apr 22 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
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  Data: A small molecule PKCε inhibitor reduces hyperalgesia induced by paclitaxel or opioid withdrawal.
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  Data: <searchLink fieldCode="AU" term="%22Gregory-Flores+A%22">Gregory-Flores A</searchLink>; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Bonet+IJ%22">Bonet IJ</searchLink>; Department of Oral and Maxillofacial Surgery, UCSF Pain and Addiction Research Center, and.; Department of Medicine, Division of Neuroscience, UCSF, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Desaivre+S%22">Desaivre S</searchLink>; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Levine+JD%22">Levine JD</searchLink>; Department of Oral and Maxillofacial Surgery, UCSF Pain and Addiction Research Center, and.; Department of Medicine, Division of Neuroscience, UCSF, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22McHardy+SF%22">McHardy SF</searchLink>; Department of Chemistry, Center for Innovative Drug Discovery, and.<br /><searchLink fieldCode="AU" term="%22de+Kraker+HC%22">de Kraker HC</searchLink>; Department of Chemistry, Center for Innovative Drug Discovery, and.<br /><searchLink fieldCode="AU" term="%22Clanton+NA%22">Clanton NA</searchLink>; Voelcker Preclinical Pharmacology Core, Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22LoCoco+PM%22">LoCoco PM</searchLink>; Voelcker Preclinical Pharmacology Core, Department of Chemistry, University of Texas at San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Russell+NM%22">Russell NM</searchLink>; Division of Pharmacology and Toxicology, College of Pharmacy.<br /><searchLink fieldCode="AU" term="%22Fleischer+C%22">Fleischer C</searchLink>; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Messing+RO%22">Messing RO</searchLink>; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.; Division of Pharmacology and Toxicology, College of Pharmacy.; Department of Neurology and the Mulva Clinic for the Neurosciences, Dell Medical School, and.<br /><searchLink fieldCode="AU" term="%22Marinelli+M%22">Marinelli M</searchLink>; Institute for Neuroscience and.; Department of Neuroscience and the Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin, Austin, Texas, USA.; Division of Pharmacology and Toxicology, College of Pharmacy.; Department of Neurology and the Mulva Clinic for the Neurosciences, Dell Medical School, and.; Department of Psychiatry and Behavioral Sciences, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2025 Apr 22; Vol. 10 (8). <i>Date of Electronic Publication: </i>2025 Apr 22 (<i>Print Publication: </i>2025).
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