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Population Pharmacokinetics of Tarlatamab, a Half-Life Extended DLL3-Directed Bispecific T-Cell Engager in Patients with Previously Treated Small Cell Lung Cancer.

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Title: Population Pharmacokinetics of Tarlatamab, a Half-Life Extended DLL3-Directed Bispecific T-Cell Engager in Patients with Previously Treated Small Cell Lung Cancer.
Authors: Kong S; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA., Minocha M; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA., Chen PW; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA., Martinez P; Clinical Development Oncology at Amgen, Thousand Oaks, USA., Anderson ES; Clinical Development Oncology at Amgen, Thousand Oaks, USA., Parkes A; Clinical Development Oncology at Amgen, Thousand Oaks, USA., Houk BE; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA., Lin CW; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA. clin04@amgen.com.
Source: Clinical pharmacokinetics [Clin Pharmacokinet] 2025 May; Vol. 64 (5), pp. 729-741. Date of Electronic Publication: 2025 Apr 22.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Population Pharmacokinetics of Tarlatamab, a Half-Life Extended DLL3-Directed Bispecific T-Cell Engager in Patients with Previously Treated Small Cell Lung Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Kong+S%22">Kong S</searchLink>; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Minocha+M%22">Minocha M</searchLink>; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Chen+PW%22">Chen PW</searchLink>; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+P%22">Martinez P</searchLink>; Clinical Development Oncology at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+ES%22">Anderson ES</searchLink>; Clinical Development Oncology at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Parkes+A%22">Parkes A</searchLink>; Clinical Development Oncology at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Houk+BE%22">Houk BE</searchLink>; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA.<br /><searchLink fieldCode="AU" term="%22Lin+CW%22">Lin CW</searchLink>; Clinical Pharmacology Modeling and Simulation at Amgen, Thousand Oaks, USA. clin04@amgen.com.
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  Data: <searchLink fieldCode="JN" term="%227606849%22">Clinical pharmacokinetics</searchLink> [Clin Pharmacokinet] 2025 May; Vol. 64 (5), pp. 729-741. <i>Date of Electronic Publication: </i>2025 Apr 22.
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        Value: 10.1007/s40262-025-01499-z
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      – TitleFull: Population Pharmacokinetics of Tarlatamab, a Half-Life Extended DLL3-Directed Bispecific T-Cell Engager in Patients with Previously Treated Small Cell Lung Cancer.
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              Text: 2025 May
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