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Alginate oligosaccharide prevents renal ischemia-reperfusion injury in rats via MRC1-mediated pathway.

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Title: Alginate oligosaccharide prevents renal ischemia-reperfusion injury in rats via MRC1-mediated pathway.
Authors: Liang BE; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Long LS; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Wu XY; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Huang MY; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Lai Y; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Yuan X; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Wang MH; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Li M; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Zheng QQ; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Zhang HL; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Chen MC; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Liu ZD; Haitang (Jiangsu) Biotechnology Co Ltd, Nantong, 226100, China., Geng X; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China., Lyu QQ; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China., Wang WD; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China., Liu QH; Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, NHC Key Laboratory of Clinical Nephrology (Sun Yat-sen University) and Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, 510080, China. liuqhua6@mail.sysu.edu.cn.; Department of Nephrology, Jieyang People's Hospital, Jieyang, 522000, China. liuqhua6@mail.sysu.edu.cn., Liu WZ; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China. liuweizhi@ouc.edu.cn.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China. liuweizhi@ouc.edu.cn., Li CL; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lichl3@mail.sysu.edu.cn.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lichl3@mail.sysu.edu.cn.
Source: Acta pharmacologica Sinica [Acta Pharmacol Sin] 2025 Sep; Vol. 46 (9), pp. 2450-2467. Date of Electronic Publication: 2025 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 100956087 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7254 (Electronic) Linking ISSN: 16714083 NLM ISO Abbreviation: Acta Pharmacol Sin Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Alginate oligosaccharide prevents renal ischemia-reperfusion injury in rats via MRC1-mediated pathway.
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  Data: <searchLink fieldCode="AU" term="%22Liang+BE%22">Liang BE</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Long+LS%22">Long LS</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Wu+XY%22">Wu XY</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Huang+MY%22">Huang MY</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Lai+Y%22">Lai Y</searchLink>; Department of Pharmacology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Yuan+X%22">Yuan X</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Wang+MH%22">Wang MH</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Zheng+QQ%22">Zheng QQ</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Zhang+HL%22">Zhang HL</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Chen+MC%22">Chen MC</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Liu+ZD%22">Liu ZD</searchLink>; Haitang (Jiangsu) Biotechnology Co Ltd, Nantong, 226100, China.<br /><searchLink fieldCode="AU" term="%22Geng+X%22">Geng X</searchLink>; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China.<br /><searchLink fieldCode="AU" term="%22Lyu+QQ%22">Lyu QQ</searchLink>; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China.<br /><searchLink fieldCode="AU" term="%22Wang+WD%22">Wang WD</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.; Department of Pathophysiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.<br /><searchLink fieldCode="AU" term="%22Liu+QH%22">Liu QH</searchLink>; Department of Nephrology, The First Affiliated Hospital, Sun Yat-sen University, NHC Key Laboratory of Clinical Nephrology (Sun Yat-sen University) and Guangdong Provincial Key Laboratory of Nephrology, Guangzhou, 510080, China. liuqhua6@mail.sysu.edu.cn.; Department of Nephrology, Jieyang People's Hospital, Jieyang, 522000, China. liuqhua6@mail.sysu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Liu+WZ%22">Liu WZ</searchLink>; Fang Zongxi Center, MoE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences, Ocean University of China, Qingdao, 266003, China. liuweizhi@ouc.edu.cn.; Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao, 266237, China. liuweizhi@ouc.edu.cn.<br /><searchLink fieldCode="AU" term="%22Li+CL%22">Li CL</searchLink>; Institute of Hypertension, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lichl3@mail.sysu.edu.cn.; Department of Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China. lichl3@mail.sysu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22100956087%22">Acta pharmacologica Sinica</searchLink> [Acta Pharmacol Sin] 2025 Sep; Vol. 46 (9), pp. 2450-2467. <i>Date of Electronic Publication: </i>2025 Apr 22.
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