FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein.
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| Title: | FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein. |
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| Authors: | Kisalu NK; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Silva Pereira LD; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Herman JD; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA., Asokan M; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Ernste K; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Merriam J; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Liu C; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., DeMouth ME; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Pegu A; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Lofgren M; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Dillon M; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Bonilla B; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., MacVicar R; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA., Zur Y; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA., Kiyuka P; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Flores-Garcia Y; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Chakraborty S; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine and Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94305, USA., Nikolaeva D; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA., Ogwang R; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Flynn B; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Francica J; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Pierson TC; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Koup RA; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA., Zavala F; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA., Wang TT; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine and Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94305, USA., Alter G; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA., Idris AH; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA., Seder RA; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2025 Apr 23; Vol. 17 (795), pp. eadk6745. Date of Electronic Publication: 2025 Apr 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40267218 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kisalu+NK%22">Kisalu NK</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Silva+Pereira+LD%22">Silva Pereira LD</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Herman+JD%22">Herman JD</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Asokan+M%22">Asokan M</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Ernste+K%22">Ernste K</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Merriam+J%22">Merriam J</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22DeMouth+ME%22">DeMouth ME</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Pegu+A%22">Pegu A</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Lofgren+M%22">Lofgren M</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Dillon+M%22">Dillon M</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Bonilla+B%22">Bonilla B</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22MacVicar+R%22">MacVicar R</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Zur+Y%22">Zur Y</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Kiyuka+P%22">Kiyuka P</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Flores-Garcia+Y%22">Flores-Garcia Y</searchLink>; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Chakraborty+S%22">Chakraborty S</searchLink>; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine and Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Nikolaeva+D%22">Nikolaeva D</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.; Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Ogwang+R%22">Ogwang R</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Flynn+B%22">Flynn B</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Francica+J%22">Francica J</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Pierson+TC%22">Pierson TC</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Koup+RA%22">Koup RA</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Zavala+F%22">Zavala F</searchLink>; Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Wang+TT%22">Wang TT</searchLink>; Institute for Immunity, Transplantation, and Infection, Stanford University School of Medicine and Department of Medicine, Division of Infectious Diseases, Stanford University, Stanford, CA 94305, USA.<br /><searchLink fieldCode="AU" term="%22Alter+G%22">Alter G</searchLink>; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Idris+AH%22">Idris AH</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Seder+RA%22">Seder RA</searchLink>; Vaccine Research Center (VRC), National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health, Bethesda, MD 20892, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2025 Apr 23; Vol. 17 (795), pp. eadk6745. <i>Date of Electronic Publication: </i>2025 Apr 23. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scitranslmed.adk6745 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eadk6745 Titles: – TitleFull: FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kisalu NK – PersonEntity: Name: NameFull: Silva Pereira LD – PersonEntity: Name: NameFull: Herman JD – PersonEntity: Name: NameFull: Asokan M – PersonEntity: Name: NameFull: Ernste K – PersonEntity: Name: NameFull: Merriam J – PersonEntity: Name: NameFull: Liu C – PersonEntity: Name: NameFull: DeMouth ME – PersonEntity: Name: NameFull: Pegu A – PersonEntity: Name: NameFull: Lofgren M – PersonEntity: Name: NameFull: Dillon M – PersonEntity: Name: NameFull: Bonilla B – PersonEntity: Name: NameFull: MacVicar R – PersonEntity: Name: NameFull: Zur Y – PersonEntity: Name: NameFull: Kiyuka P – PersonEntity: Name: NameFull: Flores-Garcia Y – PersonEntity: Name: NameFull: Chakraborty S – PersonEntity: Name: NameFull: Nikolaeva D – PersonEntity: Name: NameFull: Ogwang R – PersonEntity: Name: NameFull: Flynn B – PersonEntity: Name: NameFull: Francica J – PersonEntity: Name: NameFull: Pierson TC – PersonEntity: Name: NameFull: Koup RA – PersonEntity: Name: NameFull: Zavala F – PersonEntity: Name: NameFull: Wang TT – PersonEntity: Name: NameFull: Alter G – PersonEntity: Name: NameFull: Idris AH – PersonEntity: Name: NameFull: Seder RA IsPartOfRelationships: – BibEntity: Dates: – D: 23 M: 04 Text: 2025 Apr 23 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1946-6242 Numbering: – Type: volume Value: 17 – Type: issue Value: 795 Titles: – TitleFull: Science translational medicine Type: main |
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