Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction.

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Title: Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction.
Authors: Tatekoshi Y; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Mahmoodzadeh A; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Shapiro JS; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Liu M; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Bianco GM; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Tatekoshi A; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Camp SD; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., De Jesus A; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Koleini N; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., De La Torre S; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Wasserstrom JA; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA., Dillmann WH; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Thomson BR; Feinberg Cardiovascular and Renal Research Institute and Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Bedi KC; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Margulies KB; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Weinberg SE; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Ardehali H; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA. Electronic address: h-ardehali@northwestern.edu.
Source: Cell metabolism [Cell Metab] 2025 Jul 01; Vol. 37 (7), pp. 1584-1600.e10. Date of Electronic Publication: 2025 Apr 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101233170 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-7420 (Electronic) Linking ISSN: 15504131 NLM ISO Abbreviation: Cell Metab Subsets: MEDLINE
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  Data: Protein O-GlcNAcylation and hexokinase mitochondrial dissociation drive heart failure with preserved ejection fraction.
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  Data: <searchLink fieldCode="AU" term="%22Tatekoshi+Y%22">Tatekoshi Y</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Mahmoodzadeh+A%22">Mahmoodzadeh A</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Shapiro+JS%22">Shapiro JS</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Bianco+GM%22">Bianco GM</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Tatekoshi+A%22">Tatekoshi A</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Camp+SD%22">Camp SD</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22De+Jesus+A%22">De Jesus A</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Koleini+N%22">Koleini N</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22De+La+Torre+S%22">De La Torre S</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Wasserstrom+JA%22">Wasserstrom JA</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Dillmann+WH%22">Dillmann WH</searchLink>; Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Thomson+BR%22">Thomson BR</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Bedi+KC%22">Bedi KC</searchLink>; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Margulies+KB%22">Margulies KB</searchLink>; Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Weinberg+SE%22">Weinberg SE</searchLink>; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.<br /><searchLink fieldCode="AU" term="%22Ardehali+H%22">Ardehali H</searchLink>; Feinberg Cardiovascular and Renal Research Institute and Department of Medicine (Cardiology), Northwestern University, Chicago, IL 60611, USA. Electronic address: h-ardehali@northwestern.edu.
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