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Real-world comparative effectiveness and safety of Pertuzumab in patients with HER2+ metastatic breast cancer: A pan-Canadian population-based cohort study.

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Title: Real-world comparative effectiveness and safety of Pertuzumab in patients with HER2+ metastatic breast cancer: A pan-Canadian population-based cohort study.
Authors: Muñoz CE; Ontario Health (CCO), Toronto, Ontario, Canada.; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada., Dai WF; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Cheung WY; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; University of Calgary, Calgary, Alberta, Canada.; Oncology Outcomes (O2) Research Program, Calgary, Alberta, Canada., de Oliveira C; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada.; Centre for Addiction and Mental Health, Toronto, Ontario, Canada.; University of York, York, UK., Pataky RE; BC Cancer, Cancer Control Research, Vancouver, British Columbia, Canada., Ding PQ; University of Calgary, Calgary, Alberta, Canada.; Oncology Outcomes (O2) Research Program, Calgary, Alberta, Canada., Tran DA; Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada., Aurangzeb Z; University of Manitoba, Winnipeg, Manitoba, Canada.; Government of Manitoba, Winnipeg, Manitoba, Canada., Nagamuthu C; Ontario Health (CCO), Toronto, Ontario, Canada., Liu N; ICES, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada., Lethbridge L; Dalhousie University, Halifax, Nova Scotia, Canada., McClure C; Prince Edward Island Cancer Registry, Charlottetown, Prince Edward Island, Canada., Vriends K; Prince Edward Island Cancer Registry, Charlottetown, Prince Edward Island, Canada., Xiong H; Newfoundland and Labrador Health Services, St. John's, Newfoundland and Labrador, Canada., Folkins C; New Brunswick Institute for Research, Data and Training, University of New Brunswick, Fredericton, New Brunswick, Canada., Somayaji C; New Brunswick Institute for Research, Data and Training, University of New Brunswick, Fredericton, New Brunswick, Canada., Peacock S; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; BC Cancer, Cancer Control Research, Vancouver, British Columbia, Canada.; Faculty of Health Sciences, Simon Fraser University, Burnaby, British Columbia, Canada., Alvi R; University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Turner D; CancerCare Manitoba, Winnipeg, Manitoba, Canada.; Paul Albrechtsen Research Institute, CancerCare Manitoba, Winnipeg, Manitoba, Canada., O'Conaill C; CancerCare Manitoba, Winnipeg, Manitoba, Canada., McDonald T; New Brunswick Institute for Research, Data and Training, University of New Brunswick, Fredericton, New Brunswick, Canada., Urquhart R; Dalhousie University, Halifax, Nova Scotia, Canada., Kendell C; Dalhousie University, Halifax, Nova Scotia, Canada., Dowden J; Newfoundland and Labrador Health Services, St. John's, Newfoundland and Labrador, Canada., Strumpf E; McGill University, Montreal, Quebec, Canada., Denburg A; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; The Hospital for Sick Children, Toronto, Ontario, Canada., Beca JM; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; MORSE Consulting Inc., Toronto, Ontario, Canada., Mercer RE; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada., Tadrous M; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada.; Women's College Hospital, Toronto, Ontario, Canada., Takhar P; Ontario Health (CCO), Toronto, Ontario, Canada.; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada., Chan KKW; Ontario Health (CCO), Toronto, Ontario, Canada.; Canadian Centre for Applied Research in Cancer Control, Toronto, Ontario, Canada.; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.; ICES, Toronto, Ontario, Canada.; Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Corporate Authors: CanREValue Collaboration
Source: International journal of cancer [Int J Cancer] 2025 Sep 01; Vol. 157 (5), pp. 927-940. Date of Electronic Publication: 2025 Apr 23.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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BC Cancer, Cancer Control Research, Vancouver, British Columbia, Canada.<br /><searchLink fieldCode="AU" term="%22Ding+PQ%22">Ding PQ</searchLink>; University of Calgary, Calgary, Alberta, Canada.; Oncology Outcomes (O2) Research Program, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Tran+DA%22">Tran DA</searchLink>; Saskatchewan Cancer Agency, Saskatoon, Saskatchewan, Canada.<br /><searchLink fieldCode="AU" term="%22Aurangzeb+Z%22">Aurangzeb Z</searchLink>; University of Manitoba, Winnipeg, Manitoba, Canada.; Government of Manitoba, Winnipeg, Manitoba, Canada.<br /><searchLink fieldCode="AU" term="%22Nagamuthu+C%22">Nagamuthu C</searchLink>; Ontario Health (CCO), Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Liu+N%22">Liu N</searchLink>; ICES, Toronto, Ontario, Canada.; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lethbridge+L%22">Lethbridge L</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%220042124%22">International journal of cancer</searchLink> [Int J Cancer] 2025 Sep 01; Vol. 157 (5), pp. 927-940. <i>Date of Electronic Publication: </i>2025 Apr 23.
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