Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.

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Title: Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.
Authors: Salardini A; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA., Himali JJ; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Graduate School of Biomedical Sciences, UT Health San Antonio, San Antonio, Texas, USA., Abdullah MS; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA., Chaudhari R; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA., Young V; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA., Zilli EM; Gonzaba Medical Group (private practice), San Antonio, Texas, USA., McGrath ER; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; HRB Clinical Research Facility, University of Galway, Galway, Ireland.; School of Medicine, University of Galway, Galway, Ireland., Gonzales MM; Jona Goldrich Center for Alzheimer's and Memory Disorders, Neurology Department, Cedars-Sinai Medical Center, Los Angeles, California, USA., Thibault EG; Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA., Salinas J; Department of Neurology, New York University Grossman School of Medicine, New York, New York, USA., Aparicio HJ; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Himali D; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA., Ghosh S; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA., Buckley RF; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.; Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston, Massachusetts, USA., Satizabal CL; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA., Johnson KA; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA., DeCarli C; Department of Neurology, University of California at Davis, Sacramento, California, USA., Fakhri GE; Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA., Vasan RS; University of Texas School of Public Health, San Antonio Campus, San Antonio, Texas, USA., Beiser AS; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Seshadri S; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70179.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
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  Data: Elevated serum cortisol associated with early-detected increase of brain amyloid deposition in Alzheimer's disease imaging biomarkers among menopausal women: The Framingham Heart Study.
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  Data: <searchLink fieldCode="AU" term="%22Salardini+A%22">Salardini A</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Himali+JJ%22">Himali JJ</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Graduate School of Biomedical Sciences, UT Health San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Abdullah+MS%22">Abdullah MS</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Chaudhari+R%22">Chaudhari R</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Young+V%22">Young V</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Zilli+EM%22">Zilli EM</searchLink>; Gonzaba Medical Group (private practice), San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22McGrath+ER%22">McGrath ER</searchLink>; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; 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NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Ghosh+S%22">Ghosh S</searchLink>; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Buckley+RF%22">Buckley RF</searchLink>; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.; Center for Alzheimer Research and Treatment, Brigham and Women's Hospital, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Satizabal+CL%22">Satizabal CL</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Population Health Sciences, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+KA%22">Johnson KA</searchLink>; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22DeCarli+C%22">DeCarli C</searchLink>; Department of Neurology, University of California at Davis, Sacramento, California, USA.<br /><searchLink fieldCode="AU" term="%22Fakhri+GE%22">Fakhri GE</searchLink>; Department of Radiology, Massachusetts General Hospital/Harvard Medical School, Boston, Massachusetts, USA.; Department of Radiology & Biomedical Imaging, Yale University, New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Vasan+RS%22">Vasan RS</searchLink>; University of Texas School of Public Health, San Antonio Campus, San Antonio, Texas, USA.<br /><searchLink fieldCode="AU" term="%22Beiser+AS%22">Beiser AS</searchLink>; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Seshadri+S%22">Seshadri S</searchLink>; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, Texas, USA.; Department of Neurology, UT Health San Antonio, San Antonio, Texas, USA.; NHLBI's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Neurology, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
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