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Drug repurposing of 6-AZA-UTP and itraconazole reveals novel B3GALT5 inhibitors for pancreatic cancer.

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Title: Drug repurposing of 6-AZA-UTP and itraconazole reveals novel B3GALT5 inhibitors for pancreatic cancer.
Authors: Botcha L; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC., Sehar M; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC., Cheng YC; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC., Zhang SC; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC., Khan Jadoon MS; Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Chuang PK; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC. Electronic address: pkchuang@mail.nsysu.edu.tw.
Source: Bioorganic chemistry [Bioorg Chem] 2025 Jun 15; Vol. 160, pp. 108464. Date of Electronic Publication: 2025 Apr 10.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Drug repurposing of 6-AZA-UTP and itraconazole reveals novel B3GALT5 inhibitors for pancreatic cancer.
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  Data: <searchLink fieldCode="AU" term="%22Botcha+L%22">Botcha L</searchLink>; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Sehar+M%22">Sehar M</searchLink>; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Cheng+YC%22">Cheng YC</searchLink>; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Zhang+SC%22">Zhang SC</searchLink>; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC.<br /><searchLink fieldCode="AU" term="%22Khan+Jadoon+MS%22">Khan Jadoon MS</searchLink>; Department of Pharmacy, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan.<br /><searchLink fieldCode="AU" term="%22Chuang+PK%22">Chuang PK</searchLink>; Institute of Biomedical Sciences, National Sun Yat-Sen University Kaohsiung, 804, Taiwan, ROC. Electronic address: pkchuang@mail.nsysu.edu.tw.
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  Data: <searchLink fieldCode="JN" term="%221303703%22">Bioorganic chemistry</searchLink> [Bioorg Chem] 2025 Jun 15; Vol. 160, pp. 108464. <i>Date of Electronic Publication: </i>2025 Apr 10.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>1303703 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2120 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200452068%22">00452068 </searchLink><i>NLM ISO Abbreviation: </i>Bioorg Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.bioorg.2025.108464
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              Text: 2025 Jun 15
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