Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias.
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| Title: | Mis-splicing-derived neoantigens and cognate TCRs in splicing factor mutant leukemias. |
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| Authors: | Kim WJ; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Crosse EI; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, WA, USA., De Neef E; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Etxeberria I; Human Oncology and Pathogenesis Program, MSK, New York, NY, USA., Sabio EY; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Wang E; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Bewersdorf JP; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Lin KT; Codify Therapeutics, Cambridge, MA, USA., Lu SX; Department of Medicine, Division of Hematology, Stanford University, Palo Alto, CA, USA., Belleville A; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, WA, USA., Fox N; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Castro C; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Zhang P; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Fujino T; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Lewis J; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Rahman J; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Zhang B; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Winick JH; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Lewis AM; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Stanley RF; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., DeWolf S; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Urben BM; Single-cell Analytics Innovation Laboratory, MSK, New York, NY, USA., Takizawa M; Single-cell Analytics Innovation Laboratory, MSK, New York, NY, USA., Krause T; Single-cell Analytics Innovation Laboratory, MSK, New York, NY, USA., Molina H; Proteomics Resource Center, Rockefeller University, New York, NY, USA., Chaligne R; Single-cell Analytics Innovation Laboratory, MSK, New York, NY, USA., Koppikar P; Department of Hematopoietic Biology and Malignancy, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Molldrem J; Department of Hematopoietic Biology and Malignancy, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gigoux M; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Sandra and Edward Meyer Cancer Center, Weill Cornell Medical Center, New York, NY, USA., Merghoub T; Swim Across America and Ludwig Collaborative Laboratory, Department of Pharmacology, Sandra and Edward Meyer Cancer Center, Weill Cornell Medical Center, New York, NY, USA., Daniyan A; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA., Chandran SS; Human Oncology and Pathogenesis Program, MSK, New York, NY, USA., Greenbaum BD; Computational Oncology, Department of Epidemiology and Biostatistics, MSK, New York, NY, USA., Klebanoff CA; Human Oncology and Pathogenesis Program, MSK, New York, NY, USA; Parker Institute for Cancer Immunotherapy, New York, NY, USA. Electronic address: klebanoc@mskcc.org., Bradley RK; Public Health Sciences and Basic Sciences Divisions, Fred Hutchinson Cancer Center, Seattle, WA, USA; Department of Genome Sciences, University of Washington, Seattle, WA, USA. Electronic address: rbradley@fredhutch.org., Abdel-Wahab O; Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center (MSK), New York, NY, USA. Electronic address: abdelwao@mskcc.org. |
| Source: | Cell [Cell] 2025 Jun 26; Vol. 188 (13), pp. 3422-3440.e24. Date of Electronic Publication: 2025 Apr 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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