View in EDS

Age-sensitive response of systemic AAV-mediated gene therapy in a newly characterized feline model of mucolipidosis II.

Saved in:
Bibliographic Details
Title: Age-sensitive response of systemic AAV-mediated gene therapy in a newly characterized feline model of mucolipidosis II.
Authors: Pyne NK; Center for Gene Therapy, Nationwide Children's Hospital, Columbus, OH 43215, USA., Bagel J; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Shyng C; Gene Therapy Center, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599, USA., Odonnell P; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Miyadera K; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Srnak J; M6P Therapeutics, St. Louis, MO 63108, USA., Swain G; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Pesayco JP; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Shelton GD; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Assenmacher CA; Comparative Pathology Core, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Dickson P; Department of Pediatrics, Washington University, St. Louis, MO 63110, USA., Stern JA; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA., Flanagan-Steet H; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29646, USA., Gray SJ; Gene Therapy Center, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599, USA., Bradbury AM; Center for Gene Therapy, Nationwide Children's Hospital, Columbus, OH 43215, USA; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pediatrics, The Ohio State University, Columbus, OH 43215, USA. Electronic address: allison.bradbury@nationwidechildrens.org.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2025 Aug 06; Vol. 33 (8), pp. 3808-3821. Date of Electronic Publication: 2025 Apr 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40285357
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Age-sensitive response of systemic AAV-mediated gene therapy in a newly characterized feline model of mucolipidosis II.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Pyne+NK%22">Pyne NK</searchLink>; Center for Gene Therapy, Nationwide Children's Hospital, Columbus, OH 43215, USA.<br /><searchLink fieldCode="AU" term="%22Bagel+J%22">Bagel J</searchLink>; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Shyng+C%22">Shyng C</searchLink>; Gene Therapy Center, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Odonnell+P%22">Odonnell P</searchLink>; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Miyadera+K%22">Miyadera K</searchLink>; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Srnak+J%22">Srnak J</searchLink>; M6P Therapeutics, St. Louis, MO 63108, USA.<br /><searchLink fieldCode="AU" term="%22Swain+G%22">Swain G</searchLink>; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Pesayco+JP%22">Pesayco JP</searchLink>; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Shelton+GD%22">Shelton GD</searchLink>; Department of Pathology, School of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Assenmacher+CA%22">Assenmacher CA</searchLink>; Comparative Pathology Core, Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.<br /><searchLink fieldCode="AU" term="%22Dickson+P%22">Dickson P</searchLink>; Department of Pediatrics, Washington University, St. Louis, MO 63110, USA.<br /><searchLink fieldCode="AU" term="%22Stern+JA%22">Stern JA</searchLink>; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27607, USA.<br /><searchLink fieldCode="AU" term="%22Flanagan-Steet+H%22">Flanagan-Steet H</searchLink>; JC Self Research Institute, Greenwood Genetic Center, Greenwood, SC 29646, USA.<br /><searchLink fieldCode="AU" term="%22Gray+SJ%22">Gray SJ</searchLink>; Gene Therapy Center, University of North Carolina - Chapel Hill, Chapel Hill, NC 27599, USA.<br /><searchLink fieldCode="AU" term="%22Bradbury+AM%22">Bradbury AM</searchLink>; Center for Gene Therapy, Nationwide Children's Hospital, Columbus, OH 43215, USA; Department of Clinical Sciences and Advanced Medicine, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Pediatrics, The Ohio State University, Columbus, OH 43215, USA. Electronic address: allison.bradbury@nationwidechildrens.org.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2025 Aug 06; Vol. 33 (8), pp. 3808-3821. <i>Date of Electronic Publication: </i>2025 Apr 24.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40285357
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ymthe.2025.04.030
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 3808
    Titles:
      – TitleFull: Age-sensitive response of systemic AAV-mediated gene therapy in a newly characterized feline model of mucolipidosis II.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Pyne NK
      – PersonEntity:
          Name:
            NameFull: Bagel J
      – PersonEntity:
          Name:
            NameFull: Shyng C
      – PersonEntity:
          Name:
            NameFull: Odonnell P
      – PersonEntity:
          Name:
            NameFull: Miyadera K
      – PersonEntity:
          Name:
            NameFull: Srnak J
      – PersonEntity:
          Name:
            NameFull: Swain G
      – PersonEntity:
          Name:
            NameFull: Pesayco JP
      – PersonEntity:
          Name:
            NameFull: Shelton GD
      – PersonEntity:
          Name:
            NameFull: Assenmacher CA
      – PersonEntity:
          Name:
            NameFull: Dickson P
      – PersonEntity:
          Name:
            NameFull: Stern JA
      – PersonEntity:
          Name:
            NameFull: Flanagan-Steet H
      – PersonEntity:
          Name:
            NameFull: Gray SJ
      – PersonEntity:
          Name:
            NameFull: Bradbury AM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 06
              M: 08
              Text: 2025 Aug 06
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1525-0024
          Numbering:
            – Type: volume
              Value: 33
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Molecular therapy : the journal of the American Society of Gene Therapy
              Type: main
ResultId 1