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Multi-Target Inhibitor of ZJQ- 3 F Against AChE/BACE1/GSK3β Targets Improves the Cognitive Impairment of APP/PS1/Tau Triple-Transgenic Mouse Models of Alzheimer's Disease.

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Title: Multi-Target Inhibitor of ZJQ- 3 F Against AChE/BACE1/GSK3β Targets Improves the Cognitive Impairment of APP/PS1/Tau Triple-Transgenic Mouse Models of Alzheimer's Disease.
Authors: Wang N; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China., Li XZ; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Jiang XW; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Ning XY; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Zhou LJ; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Liu WJ; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Wu Q; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China., Wang XP; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Xing Y; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Qi ZT; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China., Xu ZH; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China., Song HT; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. sohoto@vip.163.com.; Department of Pharmacy, 900 Hospital of the Joint Logistics Team, Fuzhou, 350025, People's Republic of China. sohoto@vip.163.com., Zhao QC; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. zhaoqingchun1967@163.com.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China. zhaoqingchun1967@163.com.
Source: Molecular neurobiology [Mol Neurobiol] 2025 Sep; Vol. 62 (9), pp. 11403-11414. Date of Electronic Publication: 2025 Apr 26.
Publication Type: Journal Article
Journal Info: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-Target Inhibitor of ZJQ- 3 F Against AChE/BACE1/GSK3β Targets Improves the Cognitive Impairment of APP/PS1/Tau Triple-Transgenic Mouse Models of Alzheimer's Disease.
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  Data: <searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+XZ%22">Li XZ</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Jiang+XW%22">Jiang XW</searchLink>; School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Ning+XY%22">Ning XY</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhou+LJ%22">Zhou LJ</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liu+WJ%22">Liu WJ</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+XP%22">Wang XP</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xing+Y%22">Xing Y</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Qi+ZT%22">Qi ZT</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xu+ZH%22">Xu ZH</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Song+HT%22">Song HT</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. sohoto@vip.163.com.; Department of Pharmacy, 900 Hospital of the Joint Logistics Team, Fuzhou, 350025, People's Republic of China. sohoto@vip.163.com.<br /><searchLink fieldCode="AU" term="%22Zhao+QC%22">Zhao QC</searchLink>; Department of Clinical Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, People's Republic of China. zhaoqingchun1967@163.com.; Department of Pharmacy, General Hospital of Northern Theater Command, Shenyang, 110840, People's Republic of China. zhaoqingchun1967@163.com.
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