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Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity.

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Title: Mitochondrial Ca2+ controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity.
Authors: Weissenrieder JS; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Peura J; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Paudel U; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bhalerao N; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Weinmann N; Department of Chemistry, Millersville University, Millersville, PA, USA., Johnson C; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Wengyn M; Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-5157, USA., Drager R; Department of Chemistry, The Ohio State University, Columbus, OH, USA., Furth EE; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Simin K; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Ruscetti M; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA., Stanger BZ; Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-5157, USA., Rustgi AK; Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, NY 10032, USA., Pitarresi JR; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Electronic address: jason.pitarresi@umassmed.edu., Foskett JK; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. Electronic address: foskett@pennmedicine.upenn.edu.
Source: Cell reports [Cell Rep] 2025 May 27; Vol. 44 (5), pp. 115627. Date of Electronic Publication: 2025 Apr 25.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Mitochondrial Ca<superscript>2+</superscript> controls pancreatic cancer growth and metastasis by regulating epithelial cell plasticity.
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  Data: <searchLink fieldCode="AU" term="%22Weissenrieder+JS%22">Weissenrieder JS</searchLink>; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Peura+J%22">Peura J</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Paudel+U%22">Paudel U</searchLink>; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Bhalerao+N%22">Bhalerao N</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Weinmann+N%22">Weinmann N</searchLink>; Department of Chemistry, Millersville University, Millersville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+C%22">Johnson C</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Wengyn+M%22">Wengyn M</searchLink>; Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-5157, USA.<br /><searchLink fieldCode="AU" term="%22Drager+R%22">Drager R</searchLink>; Department of Chemistry, The Ohio State University, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Furth+EE%22">Furth EE</searchLink>; Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Simin+K%22">Simin K</searchLink>; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ruscetti+M%22">Ruscetti M</searchLink>; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Stanger+BZ%22">Stanger BZ</searchLink>; Division of Gastroenterology, Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104-5157, USA.<br /><searchLink fieldCode="AU" term="%22Rustgi+AK%22">Rustgi AK</searchLink>; Herbert Irving Comprehensive Cancer Center, Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center, New York City, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Pitarresi+JR%22">Pitarresi JR</searchLink>; Division of Hematology/Oncology, Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Molecular, Cell, and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Electronic address: jason.pitarresi@umassmed.edu.<br /><searchLink fieldCode="AU" term="%22Foskett+JK%22">Foskett JK</searchLink>; Department of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA; Department of Cell and Developmental Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. Electronic address: foskett@pennmedicine.upenn.edu.
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  Data: <searchLink fieldCode="JN" term="%22101573691%22">Cell reports</searchLink> [Cell Rep] 2025 May 27; Vol. 44 (5), pp. 115627. <i>Date of Electronic Publication: </i>2025 Apr 25.
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