View in EDS

Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.

Saved in:
Bibliographic Details
Title: Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.
Authors: Niosi M; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut. Electronic address: Mark.Niosi@pfizer.com., Zhang S; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Burchett W; Global Biometrics and Data Management, Pfizer Worldwide Research and Development, Groton, Connecticut., Heck CJS; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Goetz GH; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Federico JJ; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Gernhardt S; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Jordan S; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Gilbert AM; Medicinal Chemistry, Pfizer Worldwide Research and Development, Groton, Connecticut., Calabrese MF; Discovery Sciences, Pfizer Worldwide Research and Development, Groton, Connecticut., Obach RS; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut., Steyn SJ; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, Massachusetts.
Source: Drug metabolism and disposition: the biological fate of chemicals [Drug Metab Dispos] 2025 May; Vol. 53 (5), pp. 100066. Date of Electronic Publication: 2025 Mar 19.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Pharmacology and Experimental Therapeutics, etc.] Country of Publication: Netherlands NLM ID: 9421550 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-009X (Electronic) Linking ISSN: 00909556 NLM ISO Abbreviation: Drug Metab Dispos Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 40286535
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Niosi+M%22">Niosi M</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut. Electronic address: Mark.Niosi@pfizer.com.<br /><searchLink fieldCode="AU" term="%22Zhang+S%22">Zhang S</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Burchett+W%22">Burchett W</searchLink>; Global Biometrics and Data Management, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Heck+CJS%22">Heck CJS</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Goetz+GH%22">Goetz GH</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Federico+JJ%22">Federico JJ</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Gernhardt+S%22">Gernhardt S</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Jordan+S%22">Jordan S</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Gilbert+AM%22">Gilbert AM</searchLink>; Medicinal Chemistry, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Calabrese+MF%22">Calabrese MF</searchLink>; Discovery Sciences, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Obach+RS%22">Obach RS</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, Connecticut.<br /><searchLink fieldCode="AU" term="%22Steyn+SJ%22">Steyn SJ</searchLink>; Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, Massachusetts.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%229421550%22">Drug metabolism and disposition: the biological fate of chemicals</searchLink> [Drug Metab Dispos] 2025 May; Vol. 53 (5), pp. 100066. <i>Date of Electronic Publication: </i>2025 Mar 19.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Pharmacology+and+Experimental+Therapeutics%2C+etc%2E]%22">American Society for Pharmacology and Experimental Therapeutics, etc.] </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>9421550 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-009X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200909556%22">00909556 </searchLink><i>NLM ISO Abbreviation: </i>Drug Metab Dispos <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40286535
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.dmd.2025.100066
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 100066
    Titles:
      – TitleFull: Applications of contemporary tools to measure plasma protein binding of targeted protein degraders.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Niosi M
      – PersonEntity:
          Name:
            NameFull: Zhang S
      – PersonEntity:
          Name:
            NameFull: Burchett W
      – PersonEntity:
          Name:
            NameFull: Heck CJS
      – PersonEntity:
          Name:
            NameFull: Goetz GH
      – PersonEntity:
          Name:
            NameFull: Federico JJ
      – PersonEntity:
          Name:
            NameFull: Gernhardt S
      – PersonEntity:
          Name:
            NameFull: Jordan S
      – PersonEntity:
          Name:
            NameFull: Gilbert AM
      – PersonEntity:
          Name:
            NameFull: Calabrese MF
      – PersonEntity:
          Name:
            NameFull: Obach RS
      – PersonEntity:
          Name:
            NameFull: Steyn SJ
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 05
              Text: 2025 May
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 1521-009X
          Numbering:
            – Type: volume
              Value: 53
            – Type: issue
              Value: 5
          Titles:
            – TitleFull: Drug metabolism and disposition: the biological fate of chemicals
              Type: main
ResultId 1