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Population pharmacokinetic analysis of the interaction of digoxin with N-desethylamiodarone in patients with atrial fibrillation and heart failure.

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Title: Population pharmacokinetic analysis of the interaction of digoxin with N-desethylamiodarone in patients with atrial fibrillation and heart failure.
Authors: Hirai T; Department of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.; Department of Pharmacy, Institute of Science Tokyo Hospital, Tokyo, Japan., Kasai H; Keio University, Keio Frontier Research & Education Collaborative Square (K-FRECS) at Tonomachi, Kanagawa, Japan., Shiga T; Department of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.; Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
Source: British journal of clinical pharmacology [Br J Clin Pharmacol] 2025 Oct; Vol. 91 (10), pp. 2827-2835. Date of Electronic Publication: 2025 Apr 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Population pharmacokinetic analysis of the interaction of digoxin with N-desethylamiodarone in patients with atrial fibrillation and heart failure.
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  Data: <searchLink fieldCode="AU" term="%22Hirai+T%22">Hirai T</searchLink>; Department of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.; Department of Pharmacy, Institute of Science Tokyo Hospital, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Kasai+H%22">Kasai H</searchLink>; Keio University, Keio Frontier Research & Education Collaborative Square (K-FRECS) at Tonomachi, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Shiga+T%22">Shiga T</searchLink>; Department of Clinical Pharmacology and Therapeutics, The Jikei University School of Medicine, Tokyo, Japan.; Department of Cardiology, Tokyo Women's Medical University, Tokyo, Japan.
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  Data: <searchLink fieldCode="JN" term="%227503323%22">British journal of clinical pharmacology</searchLink> [Br J Clin Pharmacol] 2025 Oct; Vol. 91 (10), pp. 2827-2835. <i>Date of Electronic Publication: </i>2025 Apr 27.
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        Value: 10.1002/bcp.70075
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        StartPage: 2827
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      – TitleFull: Population pharmacokinetic analysis of the interaction of digoxin with N-desethylamiodarone in patients with atrial fibrillation and heart failure.
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              Text: 2025 Oct
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