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Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.

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Title: Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.
Authors: Xie L; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; School of Medicine, Tsinghua University, Beijing, China., Zhu Y; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA.; School of Medicine, Tsinghua University, Beijing, China., Hurtle BT; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA., Wright M; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University,, Chicago, IL, USA., Robinson JL; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Mauna JC; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA., Brown EE; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Integrated Systems Biology PhD Program, University of Pittsburgh, Pittsburgh, PA, USA., Ngo M; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Human Genetics PhD Program, University of Pittsburgh, Pittsburgh, PA., Bergmann CA; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA., Xu J; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Interdisciplinary Biomedical PhD Program, Molecular Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Merjane J; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA., Gleixner AM; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA., Grigorean G; Department of Proteomics, University of California, Davis, CA, USA., Liu F; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Rossoll W; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Lee EB; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kiskinis E; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University,, Chicago, IL, USA., Chikina M; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA., Donnelly CJ; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Apr 09. Date of Electronic Publication: 2025 Apr 09.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Context-dependent Interactors Regulate TDP-43 Dysfunction in ALS/FTLD.
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  Data: <searchLink fieldCode="AU" term="%22Xie+L%22">Xie L</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; School of Medicine, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+Y%22">Zhu Y</searchLink>; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA.; School of Medicine, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Hurtle+BT%22">Hurtle BT</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Wright+M%22">Wright M</searchLink>; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University,, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Robinson+JL%22">Robinson JL</searchLink>; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Mauna+JC%22">Mauna JC</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Brown+EE%22">Brown EE</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Integrated Systems Biology PhD Program, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Ngo+M%22">Ngo M</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Human Genetics PhD Program, University of Pittsburgh, Pittsburgh, PA.<br /><searchLink fieldCode="AU" term="%22Bergmann+CA%22">Bergmann CA</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.; Interdisciplinary Biomedical PhD Program, Molecular Pathology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Merjane+J%22">Merjane J</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Gleixner+AM%22">Gleixner AM</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Grigorean+G%22">Grigorean G</searchLink>; Department of Proteomics, University of California, Davis, CA, USA.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Rossoll+W%22">Rossoll W</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Lee+EB%22">Lee EB</searchLink>; Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Institute on Aging, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Kiskinis+E%22">Kiskinis E</searchLink>; The Ken & Ruth Davee Department of Neurology, Feinberg School of Medicine, Northwestern University,, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Chikina+M%22">Chikina M</searchLink>; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Donnelly+CJ%22">Donnelly CJ</searchLink>; Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.; LiveLikeLou Center for ALS Research, University of Pittsburgh, Pittsburgh, PA, USA.
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