Validation of the Chick Chorioallantoic Membrane (CAM) Model for Biocompatibility Analysis of Biomaterials in the Context of the 3R-cascade: A Pilot Study.

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Title: Validation of the Chick Chorioallantoic Membrane (CAM) Model for Biocompatibility Analysis of Biomaterials in the Context of the 3R-cascade: A Pilot Study.
Authors: Barbeck M; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany; mike.barbeck@med.uni-rostock.de., Huebner K; Experimental Tumor Pathology, Institute of Pathology, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany., Burkhardt K; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany., Andreeva T; Faculty for Applied Chemistry, Reutlingen University, Reutlingen, Germany., Krastev R; Faculty for Applied Chemistry, Reutlingen University, Reutlingen, Germany., Schnettler R; University Medical Centre, Justus Liebig University of Giessen, Giessen, Germany., Stojanovic S; Department for Cell and Tissue Engineering, Scientific Research Center for Biomedicine, Faculty of Medicine, University of Niš, Niš, Serbia.; Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, Niš, Serbia., Najman S; Department for Cell and Tissue Engineering, Scientific Research Center for Biomedicine, Faculty of Medicine, University of Niš, Niš, Serbia.; Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, Niš, Serbia., Jung O; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany., Schneider-Stock R; Experimental Tumor Pathology, Institute of Pathology, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.
Source: In vivo (Athens, Greece) [In Vivo] 2025 May-Jun; Vol. 39 (3), pp. 1740-1750.
Publication Type: Journal Article
Journal Info: Publisher: International Institute of Anticancer Research Country of Publication: Greece NLM ID: 8806809 Publication Model: Print Cited Medium: Internet ISSN: 1791-7549 (Electronic) Linking ISSN: 0258851X NLM ISO Abbreviation: In Vivo Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Barbeck+M%22">Barbeck M</searchLink>; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany; mike.barbeck@med.uni-rostock.de.<br /><searchLink fieldCode="AU" term="%22Huebner+K%22">Huebner K</searchLink>; Experimental Tumor Pathology, Institute of Pathology, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Burkhardt+K%22">Burkhardt K</searchLink>; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Andreeva+T%22">Andreeva T</searchLink>; Faculty for Applied Chemistry, Reutlingen University, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Krastev+R%22">Krastev R</searchLink>; Faculty for Applied Chemistry, Reutlingen University, Reutlingen, Germany.<br /><searchLink fieldCode="AU" term="%22Schnettler+R%22">Schnettler R</searchLink>; University Medical Centre, Justus Liebig University of Giessen, Giessen, Germany.<br /><searchLink fieldCode="AU" term="%22Stojanovic+S%22">Stojanovic S</searchLink>; Department for Cell and Tissue Engineering, Scientific Research Center for Biomedicine, Faculty of Medicine, University of Niš, Niš, Serbia.; Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, Niš, Serbia.<br /><searchLink fieldCode="AU" term="%22Najman+S%22">Najman S</searchLink>; Department for Cell and Tissue Engineering, Scientific Research Center for Biomedicine, Faculty of Medicine, University of Niš, Niš, Serbia.; Department of Biology and Human Genetics, Faculty of Medicine, University of Niš, Niš, Serbia.<br /><searchLink fieldCode="AU" term="%22Jung+O%22">Jung O</searchLink>; Clinic and Policlinic for Dermatology and Venereology, University Medical Center Rostock, Rostock, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider-Stock+R%22">Schneider-Stock R</searchLink>; Experimental Tumor Pathology, Institute of Pathology, Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.; Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, FAU Erlangen-Nürnberg, Erlangen, Germany.
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              Text: 2025 May-Jun
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