Intracellular metabolic gradients dictate dependence on exogenous pyruvate.

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Title: Intracellular metabolic gradients dictate dependence on exogenous pyruvate.
Authors: Jackson BT; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, New York, NY, USA., Montero AM; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Chakraborty S; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Brunner JS; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Arnold PK; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Louis V. Gerstner Jr. Graduate School of Biomedical Sciences, New York, NY, USA., Bridgeman AE; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Todorova PK; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Paras KI; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Weill Cornell Graduate School of Medical Sciences, Cornell University, New York, NY, USA., Finley LWS; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. finleyl@mskcc.org.
Source: Nature metabolism [Nat Metab] 2025 Jun; Vol. 7 (6), pp. 1168-1182. Date of Electronic Publication: 2025 Apr 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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        Value: 10.1038/s42255-025-01289-8
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              Text: 2025 Jun
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