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Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics.

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Title: Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics.
Authors: Nicolson PLR; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Montague SJ; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Buka RJ; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Calvert A; H&I, NHS Blood and Transplant, Bristol, UK., Sheppard JI; Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Zhang Y; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada., Wang JJ; Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.; Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia, Australia., Sharman J; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK., Hassan E; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK., Harrison J; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK., Lawrence E; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK., El-Dalil P; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK., Parekh D; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.; Department of Inflammation and Ageing, College of Medicine and Health, University of Birmingham, Birmingham, UK., Osman H; Department of Virology, Birmingham Heartlands Hospital, Birmingham, UK., Gordon TP; Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.; Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia, Australia., Nazy I; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada., Warkentin TE; Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada., Lester WA; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
Source: British journal of haematology [Br J Haematol] 2025 Jun; Vol. 206 (6), pp. 1737-1742. Date of Electronic Publication: 2025 Apr 29.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0372544 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2141 (Electronic) Linking ISSN: 00071048 NLM ISO Abbreviation: Br J Haematol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Anti-PF4 mediated thrombocytopenia and thrombosis associated with acute cytomegalovirus infection displays both HIT-like and VITT-like characteristics.
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  Data: <searchLink fieldCode="AU" term="%22Nicolson+PLR%22">Nicolson PLR</searchLink>; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Montague+SJ%22">Montague SJ</searchLink>; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Buka+RJ%22">Buka RJ</searchLink>; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Calvert+A%22">Calvert A</searchLink>; H&I, NHS Blood and Transplant, Bristol, UK.<br /><searchLink fieldCode="AU" term="%22Sheppard+JI%22">Sheppard JI</searchLink>; Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+JJ%22">Wang JJ</searchLink>; Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.; Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Sharman+J%22">Sharman J</searchLink>; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Hassan+E%22">Hassan E</searchLink>; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Harrison+J%22">Harrison J</searchLink>; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Lawrence+E%22">Lawrence E</searchLink>; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22El-Dalil+P%22">El-Dalil P</searchLink>; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Parekh+D%22">Parekh D</searchLink>; Department of Critical Care, Queen Elizabeth Hospital, Birmingham, UK.; Department of Inflammation and Ageing, College of Medicine and Health, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Osman+H%22">Osman H</searchLink>; Department of Virology, Birmingham Heartlands Hospital, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Gordon+TP%22">Gordon TP</searchLink>; Department of Immunology, College of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.; Department of Immunology, SA Pathology, Flinders Medical Centre, Bedford Park, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Nazy+I%22">Nazy I</searchLink>; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Warkentin+TE%22">Warkentin TE</searchLink>; Department of Pathology and Molecular Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.; McMaster Center for Transfusion Research, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Michael G. DeGroote School of Medicine, McMaster University, Hamilton, Ontario, Canada.; Department of Medicine, Hamilton Health Sciences, Hamilton, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Lester+WA%22">Lester WA</searchLink>; Department of Haemostasis, Liaison and Transfusion Haematology, Queen Elizabeth Hospital, Birmingham, UK.; Department of Cardiovascular Sciences, College of Medicine and Health, University of Birmingham, Birmingham, UK.
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  Data: <searchLink fieldCode="JN" term="%220372544%22">British journal of haematology</searchLink> [Br J Haematol] 2025 Jun; Vol. 206 (6), pp. 1737-1742. <i>Date of Electronic Publication: </i>2025 Apr 29.
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        Text: English
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