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An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses.

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Title: An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses.
Authors: Ramesh AK; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Sivaccumar JP; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Ye X; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Zhejiang Key Laboratory of Multi-Omics in Infection and Immunity, Center for Infectious Disease Research, School of Medicine, Westlake University, Hangzhou, Zhejiang Province, China., Yang L; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA., Guo H; IGM Biosciences Inc., Mountain View, CA, USA., Chin CN; IGM Biosciences Inc., Mountain View, CA, USA., Ha S; IGM Biosciences Inc., Mountain View, CA, USA., Shiver JW; IGM Biosciences Inc., Mountain View, CA, USA., Strohl WR; IGM Biosciences Inc., Mountain View, CA, USA., Xu Y; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Du H; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Xu K; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. xu.4692@osu.edu.; Department of Microbial Infection and Immunity & Veterinary Biosciences, Ohio State University, Columbus, OH, USA. xu.4692@osu.edu., Liu X; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA. xliu65@central.uh.edu., Fu TM; IGM Biosciences Inc., Mountain View, CA, USA. tong-ming_fu@hotmail.com., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. zhiqiang.an@uth.tmc.edu.
Source: Nature communications [Nat Commun] 2025 Apr 29; Vol. 16 (1), pp. 4025. Date of Electronic Publication: 2025 Apr 29.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: An intranasally administered IgM protects against antigenically distinct subtypes of influenza A viruses.
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  Data: <searchLink fieldCode="AU" term="%22Ramesh+AK%22">Ramesh AK</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Sivaccumar+JP%22">Sivaccumar JP</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ye+X%22">Ye X</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Zhejiang Key Laboratory of Multi-Omics in Infection and Immunity, Center for Infectious Disease Research, School of Medicine, Westlake University, Hangzhou, Zhejiang Province, China.<br /><searchLink fieldCode="AU" term="%22Yang+L%22">Yang L</searchLink>; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Guo+H%22">Guo H</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Chin+CN%22">Chin CN</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ha+S%22">Ha S</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Shiver+JW%22">Shiver JW</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Strohl+WR%22">Strohl WR</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+Y%22">Xu Y</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Du+H%22">Du H</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+N%22">Zhang N</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. xu.4692@osu.edu.; Department of Microbial Infection and Immunity & Veterinary Biosciences, Ohio State University, Columbus, OH, USA. xu.4692@osu.edu.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX, USA. xliu65@central.uh.edu.<br /><searchLink fieldCode="AU" term="%22Fu+TM%22">Fu TM</searchLink>; IGM Biosciences Inc., Mountain View, CA, USA. tong-ming_fu@hotmail.com.<br /><searchLink fieldCode="AU" term="%22An+Z%22">An Z</searchLink>; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA. zhiqiang.an@uth.tmc.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Apr 29; Vol. 16 (1), pp. 4025. <i>Date of Electronic Publication: </i>2025 Apr 29.
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