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Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease.

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Title: Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease.
Authors: Hou X; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Heckman MG; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA., Fiesel FC; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA., Koga S; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Soto-Beasley AI; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Watzlawik JO; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Zhao J; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Valentino RR; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA., Johnson PW; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA., White LJ; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA., Quicksall ZS; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA., Reddy JS; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, USA., Bras J; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan, USA.; Division of Psychiatry and Behavioral Medicine, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA., Guerreiro R; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan, USA.; Division of Psychiatry and Behavioral Medicine, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA., Zhao N; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA., Bu G; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA., Dickson DW; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA., Ross OA; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA., Springer W; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70198.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide association analysis identifies APOE as a mitophagy modifier in Lewy body disease.
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  Data: <searchLink fieldCode="AU" term="%22Hou+X%22">Hou X</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Heckman+MG%22">Heckman MG</searchLink>; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Fiesel+FC%22">Fiesel FC</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Koga+S%22">Koga S</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Soto-Beasley+AI%22">Soto-Beasley AI</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Watzlawik+JO%22">Watzlawik JO</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+J%22">Zhao J</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Valentino+RR%22">Valentino RR</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+PW%22">Johnson PW</searchLink>; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22White+LJ%22">White LJ</searchLink>; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Quicksall+ZS%22">Quicksall ZS</searchLink>; Division of Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Reddy+JS%22">Reddy JS</searchLink>; Department of Quantitative Health Sciences, Mayo Clinic, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Bras+J%22">Bras J</searchLink>; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan, USA.; Division of Psychiatry and Behavioral Medicine, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Guerreiro+R%22">Guerreiro R</searchLink>; Department of Neurodegenerative Science, Van Andel Institute, Grand Rapids, Michigan, USA.; Division of Psychiatry and Behavioral Medicine, Michigan State University College of Human Medicine, Grand Rapids, Michigan, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+N%22">Zhao N</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Bu+G%22">Bu G</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Dickson+DW%22">Dickson DW</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Ross+OA%22">Ross OA</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.<br /><searchLink fieldCode="AU" term="%22Springer+W%22">Springer W</searchLink>; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Neuroscience PhD Program, Mayo Clinic Graduate School of Biomedical Sciences, Jacksonville, Florida, USA.
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  Data: <searchLink fieldCode="JN" term="%22101231978%22">Alzheimer's & dementia : the journal of the Alzheimer's Association</searchLink> [Alzheimers Dement] 2025 Apr; Vol. 21 (4), pp. e70198.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Ltd%22">John Wiley & Sons, Ltd </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101231978 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1552-5279 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215525260%22">15525260 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimers Dement <i>Subsets: </i>MEDLINE
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        Value: 10.1002/alz.70198
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              Text: 2025 Apr
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