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Skeletal muscle biomarkers of amyotrophic lateral sclerosis: a large-scale, multi-cohort proteomic study.

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Title: Skeletal muscle biomarkers of amyotrophic lateral sclerosis: a large-scale, multi-cohort proteomic study.
Authors: Dergai O; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Wuu J; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Koziczak-Holbro M; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Malaspina A; UCL Queen Square Motor Neuron Disease Center, UCL Queen Square Institute of Neurology, University College London, Queen Square, London, UK., Granit V; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Hernandez JP; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Cooley A; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA., Sachdev R; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Yu L; Novartis Disease Area X, Novartis Biomedical Research, Cambridge, MA 02139, USA., Bidinosti M; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Flotte L; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Nash M; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Jennings LL; Novartis Disease Area X, Novartis Biomedical Research, Cambridge, MA 02139, USA., Berry JD; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA., Bruijn LI; Biomarker Development, Novartis Pharmaceuticals, UK., Brachat S; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland., Benatar M; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2025 Apr 25. Date of Electronic Publication: 2025 Apr 25.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Dergai+O%22">Dergai O</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wuu+J%22">Wuu J</searchLink>; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Koziczak-Holbro+M%22">Koziczak-Holbro M</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Malaspina+A%22">Malaspina A</searchLink>; UCL Queen Square Motor Neuron Disease Center, UCL Queen Square Institute of Neurology, University College London, Queen Square, London, UK.<br /><searchLink fieldCode="AU" term="%22Granit+V%22">Granit V</searchLink>; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Hernandez+JP%22">Hernandez JP</searchLink>; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Cooley+A%22">Cooley A</searchLink>; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Sachdev+R%22">Sachdev R</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yu+L%22">Yu L</searchLink>; Novartis Disease Area X, Novartis Biomedical Research, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Bidinosti+M%22">Bidinosti M</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Flotte+L%22">Flotte L</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Nash+M%22">Nash M</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jennings+LL%22">Jennings LL</searchLink>; Novartis Disease Area X, Novartis Biomedical Research, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Berry+JD%22">Berry JD</searchLink>; Sean M. Healey and AMG Center for ALS, Massachusetts General Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bruijn+LI%22">Bruijn LI</searchLink>; Biomarker Development, Novartis Pharmaceuticals, UK.<br /><searchLink fieldCode="AU" term="%22Brachat+S%22">Brachat S</searchLink>; Novartis Diseases of Aging and Regenerative Medicine, Novartis Biomedical Research, CH-4002 Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Benatar+M%22">Benatar M</searchLink>; Department of Neurology and ALS Center, University of Miami Miller School of Medicine, Miami, FL, USA.
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