Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer's disease.
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| Title: | Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer's disease. |
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| Authors: | Tortolani D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Decandia D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Giacovazzo G; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Scipioni L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Panuccio A; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Ciaramellano F; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., Eugelio F; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Fanti F; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Latagliata EC; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., La Barbera L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Cutuli D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Compagnone D; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., D'Amelio M; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Coccurello R; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Institute for Complex Systems (ISC), National Council of Research (CNR), Rome, Italy., Oddi S; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Petrosini L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., Maccarrone M; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy. |
| Source: | Frontiers in cellular neuroscience [Front Cell Neurosci] 2025 Apr 17; Vol. 19, pp. 1571428. Date of Electronic Publication: 2025 Apr 17 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477935 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5102 (Print) Linking ISSN: 16625102 NLM ISO Abbreviation: Front Cell Neurosci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1662-5102 |
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| DOI: | 10.3389/fncel.2025.1571428 |