Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer's disease.

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Title: Chronic palmitoylethanolamide administration via slow-release subcutaneous pellets promotes neuroprotection and mitigates neuroinflammation in the Tg2576 mouse model of Alzheimer's disease.
Authors: Tortolani D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Decandia D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Giacovazzo G; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Scipioni L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy., Panuccio A; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Ciaramellano F; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., Eugelio F; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Fanti F; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., Latagliata EC; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., La Barbera L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Cutuli D; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Psychology, University Sapienza of Rome, Rome, Italy., Compagnone D; Department of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Teramo, Italy., D'Amelio M; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Coccurello R; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Institute for Complex Systems (ISC), National Council of Research (CNR), Rome, Italy., Oddi S; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Veterinary Medicine, University of Teramo, Teramo, Italy., Petrosini L; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy., Maccarrone M; European Center for Brain Research, Fondazione Santa Lucia IRCCS, Rome, Italy.; Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Source: Frontiers in cellular neuroscience [Front Cell Neurosci] 2025 Apr 17; Vol. 19, pp. 1571428. Date of Electronic Publication: 2025 Apr 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101477935 Publication Model: eCollection Cited Medium: Print ISSN: 1662-5102 (Print) Linking ISSN: 16625102 NLM ISO Abbreviation: Front Cell Neurosci Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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