An Ocular Exposure Prediction for Topical Atropine in Human Using Physiologically Based Pharmacokinetic Modeling.
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| Title: | An Ocular Exposure Prediction for Topical Atropine in Human Using Physiologically Based Pharmacokinetic Modeling. |
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| Authors: | Zheng A; Department of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, 201203, China., Han T; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, 200081, China.; Shanghai Engineering Research Center of Laser and Autostereoscopic 3d for Vision Care (20dz2255000), Shanghai, China., Bu F; Department of Pharmacy, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China., He Q; Department of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, 201203, China., Shang J; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China.; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China.; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, 200081, China.; Shanghai Engineering Research Center of Laser and Autostereoscopic 3d for Vision Care (20dz2255000), Shanghai, China., Ho PCL; School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, 47500, Bandar Sunway, Selangor Darul Ehsan, Malaysia., Xiang X; Department of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, 201203, China. xiangxq@fudan.edu.cn.; Quzhou Fudan Institute, Quzhou, 324002, Zhejiang Province, China. xiangxq@fudan.edu.cn.; National Key Laboratory of Advanced Drug Formulations for Overcoming Delivery Barriers, Shanghai, China. xiangxq@fudan.edu.cn., Zhou X; Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, 200031, China. doctzhouxingtao@163.com.; Key Laboratory of Myopia, NHC Key Laboratory of Myopia (Fudan University), Chinese Academy of Medical Sciences, 83 Fenyang Road, Shanghai, 200031, China. doctzhouxingtao@163.com.; Shanghai Research Center of Ophthalmology and Optometry, Shanghai, 200081, China. doctzhouxingtao@163.com.; Shanghai Engineering Research Center of Laser and Autostereoscopic 3d for Vision Care (20dz2255000), Shanghai, China. doctzhouxingtao@163.com., Huang T; Department of Pharmacy, Eye and ENT Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031, China. taominhuang@fudan.edu.cn. |
| Source: | The AAPS journal [AAPS J] 2025 May 02; Vol. 27 (4), pp. 89. Date of Electronic Publication: 2025 May 02. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Association of Pharmaceutical Scientists Country of Publication: United States NLM ID: 101223209 Publication Model: Electronic Cited Medium: Internet ISSN: 1550-7416 (Electronic) Linking ISSN: 15507416 NLM ISO Abbreviation: AAPS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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