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Sequential decreases in basolateral amygdala response to threat predict failure to recover from PTSD.

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Title: Sequential decreases in basolateral amygdala response to threat predict failure to recover from PTSD.
Authors: Roeckner AR; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Lin ER; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Hinrichs R; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Harnett NG; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Lebois LAM; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., van Rooij SJH; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Ely TD; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Jovanovic T; Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI, USA., Murty VP; Department of Psychology, Temple University, Philadelphia, PA, USA., Bruce SE; Department of Psychological Sciences, University of Missouri - St. Louis, St. Louis, MO, USA., House SL; Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA., Beaudoin FL; Department of Epidemiology, Brown University, Providence, RI, USA.; Department of Emergency Medicine, Brown University, Providence, RI, USA., An X; Institute for Trauma Recovery, Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Neylan TC; Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA, USA., Clifford GD; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.; Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Linnstaedt SD; Institute for Trauma Recovery, Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Germine LT; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.; The Many Brains Project, Belmont, MA, USA., Rauch SL; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, McLean Hospital, Belmont, MA, USA., Haran JP; Department of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Storrow AB; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Lewandowski C; Department of Emergency Medicine, Henry Ford Health System, Detroit, MI, USA., Musey PI; Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Hendry PL; Department of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA., Sheikh S; Department of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA., Jones CW; Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ, USA., Punches BE; Department of Emergency Medicine, Ohio State University College of Medicine, Columbus, OH, USA.; Ohio State University College of Nursing, Columbus, OH, USA., Swor RA; Department of Emergency Medicine, Oakland University William Beaumont School of Medicine, Rochester, MI, USA., Hudak LA; Department of Emergency Medicine, Emory University School of Medicine, Atlanta, GA, USA., Pascual JL; Department of Surgery, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Seamon MJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, PA, USA., Datner EM; Department of Emergency Medicine, Jefferson Einstein hospital, Jefferson Health, Philadelphia, PA, USA.; Department of Emergency Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA., Pearson C; Department of Emergency Medicine, Wayne State University, Ascension St. John Hospital, Detroit, MI, USA., Peak DA; Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA., Merchant RC; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA., Domeier RM; Department of Emergency Medicine, Trinity Health-Ann Arbor, Ypsilanti, MI, USA., Rathlev NK; Department of Emergency Medicine, University of Massachusetts Medical School-Baystate, Springfield, MA, USA., O'Neil BJ; Department of Emergency Medicine, Wayne State University, Detroit Receiving Hospital, Detroit, MI, USA., Sergot P; Department of Emergency Medicine, McGovern Medical School at UTHealth, Houston, TX, USA., Sanchez LD; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Emergency Medicine, Harvard Medical School, Boston, MA, USA., Joormann J; Department of Psychology, Yale University, New Haven, CT, USA., Sheridan JF; Division of Biosciences, Ohio State University College of Dentistry, Columbus, OH, USA.; Institute for Behavioral Medicine Research, OSU Wexner Medical Center, Columbus, OH, USA., Harte SE; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Internal Medicine-Rheumatology, University of Michigan Medical School, Ann Arbor, MI, USA., Koenen KC; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Kessler RC; Department of Health Care Policy, Harvard Medical School, Boston, MA, USA., McLean SA; Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Institute for Trauma Recovery, Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ressler KJ; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Stevens JS; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA. jennifer.stevens@emory.edu.
Source: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2025 Sep; Vol. 50 (10), pp. 1573-1582. Date of Electronic Publication: 2025 May 03.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE
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