NOX4-driven mitochondrial oxidative stress in aging promotes myocardial remodeling and increases susceptibility to ventricular tachyarrhythmia.
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| Title: | NOX4-driven mitochondrial oxidative stress in aging promotes myocardial remodeling and increases susceptibility to ventricular tachyarrhythmia. |
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| Authors: | Mondragon RR; Department of Pharmacology, University of Michigan, 1150 West Medical Center Dr., 2301 Medical Science Research Building III, Ann Arbor, MI, 48109, USA., Wang S; Department of Pharmacology, University of Michigan, 1150 West Medical Center Dr., 2301 Medical Science Research Building III, Ann Arbor, MI, 48109, USA., Stevenson MD; Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Lozhkin A; Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Vendrov AE; Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Isom LL; Department of Pharmacology, University of Michigan, 1150 West Medical Center Dr., 2301 Medical Science Research Building III, Ann Arbor, MI, 48109, USA; Department of Neurology, University of Michigan, Ann Arbor, MI, 48109, USA; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA., Runge MS; Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA., Madamanchi NR; Department of Internal Medicine, Frankel Cardiovascular Center, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: madamanc@med.umich.edu. |
| Source: | Free radical biology & medicine [Free Radic Biol Med] 2025 Aug 01; Vol. 235, pp. 294-305. Date of Electronic Publication: 2025 May 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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