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Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.

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Title: Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.
Authors: Chen Y; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Gilliland A; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Liang Q; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Han X; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Yang H; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Chan J; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada., Lévesque D; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada., Moon KM; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Daneshgar P; Department of Chemistry, University of British Columbia, Kelowna, BC, Canada., Boisvert FM; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada., Foster L; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Zandberg WF; Department of Chemistry, University of British Columbia, Kelowna, BC, Canada., Bergstrom K; Department of Biology, University of British Columbia, Kelowna, BC, Canada., Yu HB; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas, USA., Vallance BA; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
Source: Gut microbes [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2494717. Date of Electronic Publication: 2025 May 05.
Publication Type: Journal Article
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Defining enteric bacterial pathogenesis using organoids: Citrobacter rodentium uses EspC, an atypical mucinolytic protease, to penetrate mouse colonic mucus.
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Gilliland+A%22">Gilliland A</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Liang+Q%22">Liang Q</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Han+X%22">Han X</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Chan+J%22">Chan J</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lévesque+D%22">Lévesque D</searchLink>; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada.<br /><searchLink fieldCode="AU" term="%22Moon+KM%22">Moon KM</searchLink>; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Daneshgar+P%22">Daneshgar P</searchLink>; Department of Chemistry, University of British Columbia, Kelowna, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Boisvert+FM%22">Boisvert FM</searchLink>; Department of Immunology and Cell Biology, Université de Sherbrooke, Sherbrooke, Canada.<br /><searchLink fieldCode="AU" term="%22Foster+L%22">Foster L</searchLink>; Department of Biochemistry and Molecular Biology, Michael Smith Laboratories, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Zandberg+WF%22">Zandberg WF</searchLink>; Department of Chemistry, University of British Columbia, Kelowna, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Bergstrom+K%22">Bergstrom K</searchLink>; Department of Biology, University of British Columbia, Kelowna, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Yu+HB%22">Yu HB</searchLink>; Department of Microbiology, Molecular Genetics and Immunology, University of Kansas Medical Center, Kansas, USA.<br /><searchLink fieldCode="AU" term="%22Vallance+BA%22">Vallance BA</searchLink>; Division of Gastroenterology, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101495343%22">Gut microbes</searchLink> [Gut Microbes] 2025 Dec; Vol. 17 (1), pp. 2494717. <i>Date of Electronic Publication: </i>2025 May 05.
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