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Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis.

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Title: Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis.
Authors: Pitre T; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada., Pauley E; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; The Prince Charles Hospital, Rode Road, Chermside, Brisbane, Australia., Chaudhuri D; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada., Saha R; Critical Care Centre, King's College London, London, UK.; School of Immunology and Microbial Sciences, King's College London, London, UK., Rudd KE; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Villar J; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.; Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit at Hospital Universitario Dr. Negrín, Fundación Canaria Instituto de Investigación Sanitaria de Canarias, Las Palmas, Spain.; Universidad del Atlántico Medio (UNAM), Tafira Baja, Las Palmas, Spain., Berry LR; Berry Consultants LLC, Austin, USA., Lorenzi E; Berry Consultants, Austin, USA., Hills T; Department of Infectious Diseases, Te Whatu Ora Auckland, Auckland, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand., Nichol A; University College Dublin Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland.; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia., Harrison DA; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London, UK., Finfer S; The George Institute for Global Health, University of New South Wales, Sydney, Australia.; School of Public Health, Faculty of Medicine, Imperial College London, London, England., Cohen J; The George Institute for Global Health, The Wesley Hospital, Brisbane, and The University of Queensland, Brisbane, Australia., Myburgh J; The George Institute for Global Health, Sydney, Australia.; Faculty of Medicine, University of New South Wales, Sydney, Australia.; Intensive Care Unit, St George Hospital, Kogarah, Australia., Hammond N; Critical Care Program, Northern Sydney Local Health District, NHMRC Emerging Leader Fellow, Faculty of Medicine, UNSW Sydney, Sydney, Australia.; Intensive Care National Audit and Research Centre (ICNARC), London, UK., Martínez D; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain., Fernández C; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain., Antcliffe D; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK., Gordon A; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK., Scherag A; Institute of Medical Statistics, Computer and Data Sciences, Jena University Hospital-Friedrich Schiller University Jena, Jena, Germany., Bogatsch H; Institute for Medical Informatics, Statistics and Epidemiology (IMISE) and Clinical Trial Centre Leipzig, Leipzig, Germany., Brunkhorst FM; Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany., Venkatesh B; The George Institute for Global Health, University of New South Wales, Sydney, Australia.; Gold Coast University Hospital, Southport, Australia., Annane D; IHU PROMETHEUS, Comprehensive Sepsis Centre, General Intensive Care Unit, Raymond Poincaré Hospital (APHP); School of Medicine Simone Veil, University Versailles, University Paris Saclay, Paris, France., McAuley D; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; The Prince Charles Hospital, Rode Road, Chermside, Brisbane, Australia., Angus DC; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Rochwerg B; Division of Critical Care, Department of Medicine, McMaster University, Hamilton, Canada. rochwerg@mcmaster.ca., Shankar-Hari M; Centre for Inflammation Research, Institute for Repair and Regeneration, Edinburgh, UK. manu.shankar-hari@ed.ac.uk.
Source: Intensive care medicine [Intensive Care Med] 2025 May; Vol. 51 (5), pp. 917-929. Date of Electronic Publication: 2025 May 05.
Publication Type: Journal Article; Meta-Analysis; Systematic Review; Research Support, N.I.H., Extramural
Journal Info: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Corticosteroids for adult patients hospitalised with non-viral community-acquired pneumonia: a systematic review and meta-analysis.
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  Data: <searchLink fieldCode="AU" term="%22Pitre+T%22">Pitre T</searchLink>; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Pauley+E%22">Pauley E</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; The Prince Charles Hospital, Rode Road, Chermside, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Chaudhuri+D%22">Chaudhuri D</searchLink>; Division of Respirology, Department of Medicine, University of Toronto, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Saha+R%22">Saha R</searchLink>; Critical Care Centre, King's College London, London, UK.; School of Immunology and Microbial Sciences, King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Rudd+KE%22">Rudd KE</searchLink>; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Villar+J%22">Villar J</searchLink>; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.; Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Canada.; Multidisciplinary Organ Dysfunction Evaluation Research Network, Research Unit at Hospital Universitario Dr. Negrín, Fundación Canaria Instituto de Investigación Sanitaria de Canarias, Las Palmas, Spain.; Universidad del Atlántico Medio (UNAM), Tafira Baja, Las Palmas, Spain.<br /><searchLink fieldCode="AU" term="%22Berry+LR%22">Berry LR</searchLink>; Berry Consultants LLC, Austin, USA.<br /><searchLink fieldCode="AU" term="%22Lorenzi+E%22">Lorenzi E</searchLink>; Berry Consultants, Austin, USA.<br /><searchLink fieldCode="AU" term="%22Hills+T%22">Hills T</searchLink>; Department of Infectious Diseases, Te Whatu Ora Auckland, Auckland, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand.<br /><searchLink fieldCode="AU" term="%22Nichol+A%22">Nichol A</searchLink>; University College Dublin Clinical Research Centre at St Vincent's University Hospital, Dublin, Ireland.; The Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Harrison+DA%22">Harrison DA</searchLink>; Clinical Trials Unit, Intensive Care National Audit and Research Centre, London, UK.<br /><searchLink fieldCode="AU" term="%22Finfer+S%22">Finfer S</searchLink>; The George Institute for Global Health, University of New South Wales, Sydney, Australia.; School of Public Health, Faculty of Medicine, Imperial College London, London, England.<br /><searchLink fieldCode="AU" term="%22Cohen+J%22">Cohen J</searchLink>; The George Institute for Global Health, The Wesley Hospital, Brisbane, and The University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Myburgh+J%22">Myburgh J</searchLink>; The George Institute for Global Health, Sydney, Australia.; Faculty of Medicine, University of New South Wales, Sydney, Australia.; Intensive Care Unit, St George Hospital, Kogarah, Australia.<br /><searchLink fieldCode="AU" term="%22Hammond+N%22">Hammond N</searchLink>; Critical Care Program, Northern Sydney Local Health District, NHMRC Emerging Leader Fellow, Faculty of Medicine, UNSW Sydney, Sydney, Australia.; Intensive Care National Audit and Research Centre (ICNARC), London, UK.<br /><searchLink fieldCode="AU" term="%22Martínez+D%22">Martínez D</searchLink>; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Fernández+C%22">Fernández C</searchLink>; CIBER de Enfermedades Respiratorias, Instituto de Salud Carlos III, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Antcliffe+D%22">Antcliffe D</searchLink>; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Gordon+A%22">Gordon A</searchLink>; Division of Anaesthetics, Pain Medicine and Intensive Care, Department of Surgery and Cancer, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Scherag+A%22">Scherag A</searchLink>; Institute of Medical Statistics, Computer and Data Sciences, Jena University Hospital-Friedrich Schiller University Jena, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Bogatsch+H%22">Bogatsch H</searchLink>; Institute for Medical Informatics, Statistics and Epidemiology (IMISE) and Clinical Trial Centre Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Brunkhorst+FM%22">Brunkhorst FM</searchLink>; Department of Anaesthesiology and Intensive Care Medicine, Jena University Hospital, Jena, Germany.<br /><searchLink fieldCode="AU" term="%22Venkatesh+B%22">Venkatesh B</searchLink>; The George Institute for Global Health, University of New South Wales, Sydney, Australia.; Gold Coast University Hospital, Southport, Australia.<br /><searchLink fieldCode="AU" term="%22Annane+D%22">Annane D</searchLink>; IHU PROMETHEUS, Comprehensive Sepsis Centre, General Intensive Care Unit, Raymond Poincaré Hospital (APHP); School of Medicine Simone Veil, University Versailles, University Paris Saclay, Paris, France.<br /><searchLink fieldCode="AU" term="%22McAuley+D%22">McAuley D</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; The Prince Charles Hospital, Rode Road, Chermside, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Angus+DC%22">Angus DC</searchLink>; Center for Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA), Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Rochwerg+B%22">Rochwerg B</searchLink>; Division of Critical Care, Department of Medicine, McMaster University, Hamilton, Canada. rochwerg@mcmaster.ca.<br /><searchLink fieldCode="AU" term="%22Shankar-Hari+M%22">Shankar-Hari M</searchLink>; Centre for Inflammation Research, Institute for Repair and Regeneration, Edinburgh, UK. manu.shankar-hari@ed.ac.uk.
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