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Loss of lipid asymmetry facilitates plasma membrane blebbing by decreasing membrane lipid packing.

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Title: Loss of lipid asymmetry facilitates plasma membrane blebbing by decreasing membrane lipid packing.
Authors: Wang HY; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903., Rumin A; Molecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, CO 80210., Doktorova M; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Solna 171 65, Sweden., Sputay D; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903., Chan SH; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903., Wehman AM; Molecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, CO 80210.; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843., Levental KR; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903., Levental I; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 May 13; Vol. 122 (19), pp. e2417145122. Date of Electronic Publication: 2025 May 05.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Wang+HY%22">Wang HY</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.<br /><searchLink fieldCode="AU" term="%22Rumin+A%22">Rumin A</searchLink>; Molecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, CO 80210.<br /><searchLink fieldCode="AU" term="%22Doktorova+M%22">Doktorova M</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Solna 171 65, Sweden.<br /><searchLink fieldCode="AU" term="%22Sputay+D%22">Sputay D</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.<br /><searchLink fieldCode="AU" term="%22Chan+SH%22">Chan SH</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.<br /><searchLink fieldCode="AU" term="%22Wehman+AM%22">Wehman AM</searchLink>; Molecular and Cellular Biophysics Program, Department of Biological Sciences, University of Denver, Denver, CO 80210.; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX 77843.<br /><searchLink fieldCode="AU" term="%22Levental+KR%22">Levental KR</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.<br /><searchLink fieldCode="AU" term="%22Levental+I%22">Levental I</searchLink>; Department of Molecular Physiology and Biological Physics, Center for Membrane and Cell Physiology, University of Virginia, Charlottesville, VA 22903.
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